A0A0R4J2E1 · A0A0R4J2E1_HUMAN
- ProteinCat eye syndrome critical region protein 2
- GeneCECR2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1301 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | CERF complex | |
Cellular Component | euchromatin | |
Biological Process | chromatin remodeling | |
Biological Process | cochlea development | |
Biological Process | inner ear receptor cell stereocilium organization | |
Biological Process | neural fold formation | |
Biological Process | neural tube closure | |
Biological Process | single fertilization |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionA0A0R4J2E1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,731 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 239 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 363 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 422 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 1123 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-78 | Disordered | ||||
Sequence: MYKEDPVQGKSNGELSLSRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQG | ||||||
Compositional bias | 11-31 | Polar residues | ||||
Sequence: SNGELSLSRESEGQKNVSSIP | ||||||
Compositional bias | 57-78 | Polar residues | ||||
Sequence: QEENSLASEPQTRHGSQGPGQG | ||||||
Coiled coil | 163-215 | |||||
Sequence: IEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEDRAKRRKLR | ||||||
Domain | 268-338 | Bromo | ||||
Sequence: KAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYT | ||||||
Region | 373-521 | Disordered | ||||
Sequence: EKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRL | ||||||
Compositional bias | 420-440 | Polar residues | ||||
Sequence: APSSGDDQSSSSTQPPREVGT | ||||||
Region | 613-642 | Disordered | ||||
Sequence: GNHGATNQGPLGPDEKPHLGPGPSHQPRTL | ||||||
Region | 736-870 | Disordered | ||||
Sequence: GVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPG | ||||||
Compositional bias | 737-754 | Pro residues | ||||
Sequence: VPYHPHQPAHPRLPGPFP | ||||||
Compositional bias | 817-853 | Polar residues | ||||
Sequence: HPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNC | ||||||
Region | 982-1076 | Disordered | ||||
Sequence: VMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSD | ||||||
Compositional bias | 1040-1054 | Polar residues | ||||
Sequence: YACPQSFSDWQRPLH | ||||||
Compositional bias | 1056-1070 | Pro residues | ||||
Sequence: QGSPSGPPASQPPPP | ||||||
Region | 1104-1137 | Disordered | ||||
Sequence: AKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD | ||||||
Compositional bias | 1112-1137 | Basic and acidic residues | ||||
Sequence: NPGPEEEKLDESMERPESPKEFLDLD | ||||||
Region | 1259-1301 | Disordered | ||||
Sequence: YRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS | ||||||
Compositional bias | 1265-1285 | Polar residues | ||||
Sequence: QMHPVQSQASFPKTPTAATSQ |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,301
- Mass (Da)143,121
- Last updated2016-01-20 v1
- Checksum05C5ACD48906EDC0
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9BXF3 | CECR2_HUMAN | CECR2 | 1484 | ||
H0Y2Z1 | H0Y2Z1_HUMAN | CECR2 | 218 | ||
A0A087WT21 | A0A087WT21_HUMAN | CECR2 | 1442 | ||
B7WPH3 | B7WPH3_HUMAN | CECR2 | 1300 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 11-31 | Polar residues | ||||
Sequence: SNGELSLSRESEGQKNVSSIP | ||||||
Compositional bias | 57-78 | Polar residues | ||||
Sequence: QEENSLASEPQTRHGSQGPGQG | ||||||
Compositional bias | 420-440 | Polar residues | ||||
Sequence: APSSGDDQSSSSTQPPREVGT | ||||||
Compositional bias | 737-754 | Pro residues | ||||
Sequence: VPYHPHQPAHPRLPGPFP | ||||||
Compositional bias | 817-853 | Polar residues | ||||
Sequence: HPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNC | ||||||
Compositional bias | 1040-1054 | Polar residues | ||||
Sequence: YACPQSFSDWQRPLH | ||||||
Compositional bias | 1056-1070 | Pro residues | ||||
Sequence: QGSPSGPPASQPPPP | ||||||
Compositional bias | 1112-1137 | Basic and acidic residues | ||||
Sequence: NPGPEEEKLDESMERPESPKEFLDLD | ||||||
Compositional bias | 1265-1285 | Polar residues | ||||
Sequence: QMHPVQSQASFPKTPTAATSQ |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007666 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
FO681548 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |