A0A0R4IYX6 · Z687A_DANRE
- ProteinZinc finger protein 687a
- Geneznf687a
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1246 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
May be involved in transcriptional regulation.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameZinc finger protein 687a
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A0R4IYX6
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000437166 | 1-1246 | Zinc finger protein 687a | |||
Sequence: MGDMKTPDFDDLLAAFDIPDIDAKEAIQSDTHGNHNEHSSVVGKERSGSPSLRPSGSPDPPHNDPSVVSVIVKNSVHSDDKAEGNETGEFSSADESQKSPQKGPSKDSSVPTDPFIYNGLKSVSDGSTESPPSLDLAPGQHNGPLWSLSASKATGDDDKHNDAFTNHPASTFQSLPLSNHPSVSSHLISPNFSSKVDSEEAQAINGTLRAGVRRHQSEDEESEPDLGSPALVIQESPISQLCPAPKVPRMQRSPSSVFQPPSPSSPSLPVSNTQMEEPSVQHPKLHSSTNPTSLTSTNNLPVEEKDLEHIIEERDSPESPEPEISQSRTSLPSNSQGAIESKQRITREEAPQDEVMDVSMQEKVDYGAEATEGKSTEPTLVESASDAISNSASSKPLKMRIKTVKKPVVSITRTVSKAATKGGASKGSGASKVQAVARKSLQKIPRSVASPQLLSQSTKVAMLPVSTLQDASTAMLFAASRAQNQMPTALSATAVNITRTSNLPSISSSSIPGVNVRAASGQKTNTGTAKPASIVNSPGAVISRSQSSLVEAFNKILNSKNPLPSYQPDLTSLPPPEWGLRLPSTGYRCLECGDAFALERSLARHYDRRSMRIEVTCNHCSKRLAFFNKCSLLLHAREHKEKGLVMQCSHLVMSPVSVEQMIGQQDTVPIGVLSPAVSALSAIKESGVNLSQSSDHSCPECWSTFKGKQELVAHFQEVEPGGTDTCCLQCSPPMPLWNSCCAAAHRRMHQQLPPLVCPECGLICQTHELNTHLKQTCLHYSRRLGYKCACCHLVFGGVNSQNAVKTHMQTAHCEIFHKCPSCPMAFKSSSGAESHCASQHPELSESARQSKEIYKCVMCRTVFTQKSLLSVHIDTHLTKQKMHVFKCPDCNKLFTQRTSLLEHVKDTHRETSNHDGTSTQNSLVKMESSDGEEWGRDEEEDKGKVSDANSAVPRSQSWSCSQCQTHYTDKENYISHMTEQHGKELKKFPCTLCEGSFSSSSSLRRHIRVKHKGIKRVFYCQLCTGEKRSFSSKLILEKHIQAQHAGERGTATQSQAVPQFTDGADSSSEHDAGVLGGSSVEPESRLAESTLTRRIKGAPVGEQEAKGLRCMPCGFTTEDREEFLQHIVCHRDGGSGAQCQQCGACFASSSSLSRHLFISHRVRDSPSDHAEAALHTCATSVASDSAAAGGSPGSPLSVVGGLLEDGEGKHICKVCGRYFSKPADLNTHFRTHGMAFITAYKTDKPA |
Proteomic databases
Expression
Tissue specificity
Widely expressed with highest levels in kidney, spleen and ovary.
Developmental stage
Highly expressed in the initial stages of development (4-cell up to 1k-2k cell stages). Expression slightly increases again between 24 hours and 5 dpf and after 20 dpf. Up-regulated during regeneration of the caudal fin after amputation.
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 24-42 | Basic and acidic residues | ||||
Sequence: KEAIQSDTHGNHNEHSSVV | ||||||
Region | 24-387 | Disordered | ||||
Sequence: KEAIQSDTHGNHNEHSSVVGKERSGSPSLRPSGSPDPPHNDPSVVSVIVKNSVHSDDKAEGNETGEFSSADESQKSPQKGPSKDSSVPTDPFIYNGLKSVSDGSTESPPSLDLAPGQHNGPLWSLSASKATGDDDKHNDAFTNHPASTFQSLPLSNHPSVSSHLISPNFSSKVDSEEAQAINGTLRAGVRRHQSEDEESEPDLGSPALVIQESPISQLCPAPKVPRMQRSPSSVFQPPSPSSPSLPVSNTQMEEPSVQHPKLHSSTNPTSLTSTNNLPVEEKDLEHIIEERDSPESPEPEISQSRTSLPSNSQGAIESKQRITREEAPQDEVMDVSMQEKVDYGAEATEGKSTEPTLVESASDA | ||||||
Compositional bias | 89-112 | Polar residues | ||||
Sequence: EFSSADESQKSPQKGPSKDSSVPT | ||||||
Compositional bias | 121-135 | Polar residues | ||||
Sequence: KSVSDGSTESPPSLD | ||||||
Compositional bias | 165-201 | Polar residues | ||||
Sequence: TNHPASTFQSLPLSNHPSVSSHLISPNFSSKVDSEEA | ||||||
Compositional bias | 268-301 | Polar residues | ||||
Sequence: LPVSNTQMEEPSVQHPKLHSSTNPTSLTSTNNLP | ||||||
Compositional bias | 302-321 | Basic and acidic residues | ||||
Sequence: VEEKDLEHIIEERDSPESPE | ||||||
Compositional bias | 322-341 | Polar residues | ||||
Sequence: PEISQSRTSLPSNSQGAIES | ||||||
Compositional bias | 342-360 | Basic and acidic residues | ||||
Sequence: KQRITREEAPQDEVMDVSM | ||||||
Zinc finger | 587-619 | C2H2-type 1 | ||||
Sequence: YRCLECGDAFALERSLARHYDRRSMRIEVTCNH | ||||||
Zinc finger | 696-719 | C2H2-type 2; degenerate | ||||
Sequence: HSCPECWSTFKGKQELVAHFQEVE | ||||||
Zinc finger | 817-840 | C2H2-type 3 | ||||
Sequence: HKCPSCPMAFKSSSGAESHCASQH | ||||||
Zinc finger | 854-876 | C2H2-type 4 | ||||
Sequence: YKCVMCRTVFTQKSLLSVHIDTH | ||||||
Zinc finger | 885-908 | C2H2-type 5 | ||||
Sequence: FKCPDCNKLFTQRTSLLEHVKDTH | ||||||
Region | 907-953 | Disordered | ||||
Sequence: THRETSNHDGTSTQNSLVKMESSDGEEWGRDEEEDKGKVSDANSAVP | ||||||
Compositional bias | 929-947 | Basic and acidic residues | ||||
Sequence: SDGEEWGRDEEEDKGKVSD | ||||||
Zinc finger | 958-981 | C2H2-type 6 | ||||
Sequence: WSCSQCQTHYTDKENYISHMTEQH | ||||||
Zinc finger | 988-1011 | C2H2-type 7 | ||||
Sequence: FPCTLCEGSFSSSSSLRRHIRVKH | ||||||
Zinc finger | 1018-1044 | C2H2-type 8; degenerate | ||||
Sequence: FYCQLCTGEKRSFSSKLILEKHIQAQH | ||||||
Region | 1045-1093 | Disordered | ||||
Sequence: AGERGTATQSQAVPQFTDGADSSSEHDAGVLGGSSVEPESRLAESTLTR | ||||||
Compositional bias | 1046-1066 | Polar residues | ||||
Sequence: GERGTATQSQAVPQFTDGADS | ||||||
Zinc finger | 1137-1160 | C2H2-type 9 | ||||
Sequence: AQCQQCGACFASSSSLSRHLFISH | ||||||
Zinc finger | 1210-1232 | C2H2-type 10 | ||||
Sequence: HICKVCGRYFSKPADLNTHFRTH |
Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,246
- Mass (Da)134,592
- Last updated2016-01-20 v1
- Checksum93CF31FAA4A69579
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 24-42 | Basic and acidic residues | ||||
Sequence: KEAIQSDTHGNHNEHSSVV | ||||||
Compositional bias | 89-112 | Polar residues | ||||
Sequence: EFSSADESQKSPQKGPSKDSSVPT | ||||||
Compositional bias | 121-135 | Polar residues | ||||
Sequence: KSVSDGSTESPPSLD | ||||||
Compositional bias | 165-201 | Polar residues | ||||
Sequence: TNHPASTFQSLPLSNHPSVSSHLISPNFSSKVDSEEA | ||||||
Compositional bias | 268-301 | Polar residues | ||||
Sequence: LPVSNTQMEEPSVQHPKLHSSTNPTSLTSTNNLP | ||||||
Compositional bias | 302-321 | Basic and acidic residues | ||||
Sequence: VEEKDLEHIIEERDSPESPE | ||||||
Compositional bias | 322-341 | Polar residues | ||||
Sequence: PEISQSRTSLPSNSQGAIES | ||||||
Compositional bias | 342-360 | Basic and acidic residues | ||||
Sequence: KQRITREEAPQDEVMDVSM | ||||||
Compositional bias | 929-947 | Basic and acidic residues | ||||
Sequence: SDGEEWGRDEEEDKGKVSD | ||||||
Compositional bias | 1046-1066 | Polar residues | ||||
Sequence: GERGTATQSQAVPQFTDGADS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FP929011 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |