A0A0R4IVA6 · A0A0R4IVA6_DANRE

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site333
Binding site334Ca2+ (UniProtKB | ChEBI)
Binding site363Ca2+ (UniProtKB | ChEBI)
Binding site365Ca2+ (UniProtKB | ChEBI)
Active site380
Binding site414Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncalcium ion binding
Molecular Functioncalmodulin binding
Molecular Functionphosphatidylinositol phospholipase C activity
Biological Processcartilage morphogenesis
Biological Processembryonic viscerocranium morphogenesis
Biological ProcessG protein-coupled receptor signaling pathway
Biological Processlipid catabolic process
Biological Processnegative regulation of calcium ion import
Biological Processnegative regulation of vascular permeability
Biological Processphosphatidylinositol metabolic process
Biological Processphosphatidylinositol-mediated signaling
Biological Processrelease of sequestered calcium ion into cytosol

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
  • EC number

Gene names

    • Name
      plcb3
    • Synonyms
      Plcbeta3
      , she
      , si:ch211-188c22.1
      , si:zc188c22.1
      , wu:fl04b08

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A0R4IVA6
  • Secondary accessions
    • A0A8M2BDZ4

Proteomes

Organism-specific databases

Subcellular Location

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias, domain, coiled coil.

TypeIDPosition(s)Description
Region468-558Disordered
Compositional bias516-534Basic and acidic residues
Domain570-686PI-PLC Y-box
Domain689-813C2
Region862-913Disordered
Compositional bias873-890Polar residues
Compositional bias891-905Pro residues
Coiled coil1046-1114
Region1177-1216Disordered
Compositional bias1184-1199Polar residues
Region1226-1245Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,245
  • Mass (Da)
    141,928
  • Last updated
    2018-06-20 v2
  • Checksum
    480D03E87F249665
MAGAKPGVHALQLKPVSVNEVLKRGSKFIKWDEEANSTPSLITLRVDPNGFFLYWTGGTSMEAEILDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAVQDGYCKLWTDELFKLATNMLSQNASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSDKKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLSPRPEVERIFVDLGSKGKPFLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQLERDQISLMSFTKYLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCRCIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDSAKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNGGSIRRKDGTDEQSSPLNDCPLSDGDVGQLMSNGGEKLAERMAKDHDNSKSIDRGDGESDEEEEEEPIPDPKKHNNTDEGTAYSEVNATEEMSTLVNYIEPVKFKSFEVAAKRKKFFEMSSFVETKGMDTLKNSPTEFVEYNKKQMSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLAMQLNMGVFEYNGRCGYLLKPEFMRRTDKHFDPFTTDIVDGIVANTVKVKIISGQFLNDKKVGVYVEVDMFGLPADTKRKYRTKTSNNNSLDPVWDDETFVFNKVVLPTLASLRVAVYEENGKFIGHRILPVSALRPGYHYICLKNELNQPLMLPSLLVYTEVQDYIPNEHQEYAEALTNPIKHLSLLAQRESQLLALMEDPTEGGPTKQEEGDGTDSSCVTSADPIFPLPSSPTLPSVPTDLNPPPSGQKEDLVNNVLKVIEPESVDELKQHNSYLKLLKKQCKEFKELSKKHLKKMLALSKEQKTLFNQQSSELQRKRSQIEKRIRTSLKKNGSEDSVHRELNELDLELQKQMEQFREEHMQKLLVLRQGQLQMEKEVKQFHLKEANQKLKDIAIECQAAQIKKLKDVCDKEKKELQKMLDRKRLNSIVEARKAEKEIRDVNEINRKHIQESVSLIRQLEVSQGKRQEKLKALHKDILQKIEEEIPMNQARLTRDFEAELKRLPEEISQYLQELESKGSRKDSLMGQTNDGPNSGPPSNCSTPPYSSPNHSWSNIANVSSLLLDSSTSSSSAKSETDTTGVY

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A2TJ25A2TJ25_DANREplcb31244

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias516-534Basic and acidic residues
Compositional bias873-890Polar residues
Compositional bias891-905Pro residues
Compositional bias1184-1199Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL772136
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BX511143
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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