A0A0R4IEP9 · A0A0R4IEP9_DANRE
- Proteinnon-specific serine/threonine protein kinase
- Genetnika
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1332 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | convergent extension involved in gastrulation | |
Biological Process | gastrulation | |
Biological Process | MAPK cascade | |
Biological Process | neuron projection morphogenesis | |
Biological Process | regulation of cell shape | |
Biological Process | regulation of MAPK cascade |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A0R4IEP9
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 25-289 | Protein kinase | ||||
Sequence: FELVELVGNGTYGQVYKGRHVKTGQLAAIKCMDVTGEEEEEIKAEINMLKKYSHHRNIATYYGAFIKKNPPGVDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEDWTAYISREILRGLTHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVSRRNTFIGTPYWMAPEVIACDENPDATYDYKSDLWSLGITALEMAEGAPPLCELHPMRALFLIPRNAPPRLKSKKWTKRFHSFIESCLVKNHNMRPGTDQLLKHPFI | ||||||
Region | 308-345 | Disordered | ||||
Sequence: RTRKKRGERDETEYEYSGSEEEEEAMLEIGEPSSIINI | ||||||
Compositional bias | 321-335 | Acidic residues | ||||
Sequence: YEYSGSEEEEEAMLE | ||||||
Region | 407-432 | Disordered | ||||
Sequence: QQRREREARKQQEQRHRYEELRREEE | ||||||
Region | 520-933 | Disordered | ||||
Sequence: HYKDAVNPSDKPAWAKKVEERSKLNRQSSPALQHKVANRISDPSLPPRSESFSSGGMQPARTPPMHRPVEPQMAHLVPVRSHSSSMSVSQSLHDQSAKGVSAFQESLVSNRPEMPRQNSDPTSEMPPPAPRMASHEEKPDRSSPWLREDAVPPKLSGTTQVPQRTTSISPALARKNSPGNGESSGGGRSASQLIRTSNPDLRRTELSLDVALQRTSSNSSSSSSTPSSQGGSQPGSSERNQPRGSGKSEGSPVALQETSKPIQEEGRELSKPSRPADLTALAKELRELRIDEVSRPPLKLTDYSSSSEDSDSSEDEDGTVGHDGTVSVSDIPRIMPSVQGNNESFTSSHDDSLTDSYNDESKDGTLRMRENNERQRLGHGESNGFAGHGNLPDLLQQSHSPSGTPTGLNSQDLD | ||||||
Compositional bias | 563-577 | Polar residues | ||||
Sequence: SLPPRSESFSSGGMQ | ||||||
Compositional bias | 597-639 | Polar residues | ||||
Sequence: PVRSHSSSMSVSQSLHDQSAKGVSAFQESLVSNRPEMPRQNSD | ||||||
Compositional bias | 650-666 | Basic and acidic residues | ||||
Sequence: RMASHEEKPDRSSPWLR | ||||||
Compositional bias | 675-777 | Polar residues | ||||
Sequence: SGTTQVPQRTTSISPALARKNSPGNGESSGGGRSASQLIRTSNPDLRRTELSLDVALQRTSSNSSSSSSTPSSQGGSQPGSSERNQPRGSGKSEGSPVALQET | ||||||
Compositional bias | 799-815 | Basic and acidic residues | ||||
Sequence: ALAKELRELRIDEVSRP | ||||||
Compositional bias | 851-871 | Polar residues | ||||
Sequence: PRIMPSVQGNNESFTSSHDDS | ||||||
Compositional bias | 872-896 | Basic and acidic residues | ||||
Sequence: LTDSYNDESKDGTLRMRENNERQRL | ||||||
Compositional bias | 912-932 | Polar residues | ||||
Sequence: DLLQQSHSPSGTPTGLNSQDL | ||||||
Domain | 1019-1306 | CNH | ||||
Sequence: NSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLITRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGELEGCIHYKVVKYERIKFLVIALKNSVEIYAWAPKPYHKFMAFKSFTELQHRPQLVDLTVEEGQRLKVIYGSSVGFHVIDVDSGSPYDIYIPSHIQSTVTPHAIVVLPKTDGMEMLLCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKV |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,332
- Mass (Da)151,393
- Last updated2016-01-20 v1
- ChecksumF3AF8154C1634EC5
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M2BAL6 | A0A8M2BAL6_DANRE | tnika | 1419 | ||
Q7SY42 | Q7SY42_DANRE | tnika | 1303 | ||
A0A8M2BAF9 | A0A8M2BAF9_DANRE | tnika | 1413 | ||
A0A8M2BAG3 | A0A8M2BAG3_DANRE | tnika | 858 | ||
A0A8M2BAK0 | A0A8M2BAK0_DANRE | tnika | 1326 | ||
A0A8M2BAL9 | A0A8M2BAL9_DANRE | tnika | 1297 | ||
A0A8M2BAT5 | A0A8M2BAT5_DANRE | tnika | 1390 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 321-335 | Acidic residues | ||||
Sequence: YEYSGSEEEEEAMLE | ||||||
Compositional bias | 563-577 | Polar residues | ||||
Sequence: SLPPRSESFSSGGMQ | ||||||
Compositional bias | 597-639 | Polar residues | ||||
Sequence: PVRSHSSSMSVSQSLHDQSAKGVSAFQESLVSNRPEMPRQNSD | ||||||
Compositional bias | 650-666 | Basic and acidic residues | ||||
Sequence: RMASHEEKPDRSSPWLR | ||||||
Compositional bias | 675-777 | Polar residues | ||||
Sequence: SGTTQVPQRTTSISPALARKNSPGNGESSGGGRSASQLIRTSNPDLRRTELSLDVALQRTSSNSSSSSSTPSSQGGSQPGSSERNQPRGSGKSEGSPVALQET | ||||||
Compositional bias | 799-815 | Basic and acidic residues | ||||
Sequence: ALAKELRELRIDEVSRP | ||||||
Compositional bias | 851-871 | Polar residues | ||||
Sequence: PRIMPSVQGNNESFTSSHDDS | ||||||
Compositional bias | 872-896 | Basic and acidic residues | ||||
Sequence: LTDSYNDESKDGTLRMRENNERQRL | ||||||
Compositional bias | 912-932 | Polar residues | ||||
Sequence: DLLQQSHSPSGTPTGLNSQDL |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR392026 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CR848726 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CT027687 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |