A0A0R3CTK3 · A0A0R3CTK3_9PSED
- ProteinFluoride-specific ion channel FluC
- GenecrcB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids124 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 76 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 79 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A0R3CTK3
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 35-56 | Helical | |||
Transmembrane | 68-86 | Helical | |||
Transmembrane | 98-119 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length124
- Mass (Da)12,979
- Last updated2016-01-20 v1
- Checksum2A5CC2C106A5F452
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AHPN01000001 EMBL· GenBank· DDBJ | EIK61720.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DYTS01000306 EMBL· GenBank· DDBJ | HJH20449.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VWXW01000465 EMBL· GenBank· DDBJ | KAA6193982.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAAQYK010000005 EMBL· GenBank· DDBJ | NNA45739.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAAQYH010000003 EMBL· GenBank· DDBJ | NNA72580.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAAQYI010000005 EMBL· GenBank· DDBJ | NNA79271.1 EMBL· GenBank· DDBJ | Genomic DNA |