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A0A0R2SEM3 · A0A0R2SEM3_9GAMM

Function

function

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionflavin adenine dinucleotide binding
Biological ProcesstRNA methylation
Biological ProcesstRNA wobble uridine modification

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
  • Alternative names
    • Glucose-inhibited division protein A

Gene names

    • Name
      gidA
    • ORF names
      ABR69_07270

Organism names

Accessions

  • Primary accession
    A0A0R2SEM3

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-399MnmG N-terminal
Domain460-580tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal N-terninal subdomain

Sequence similarities

Belongs to the MnmG family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    589
  • Mass (Da)
    64,822
  • Last updated
    2016-01-20 v1
  • MD5 Checksum
    55EF3FDCD5FD8D9ECA868CF18C79F66C
MEYPSTFDVIVIGGGHAGTEAALASARQGVPTMLITHSIDTLGQMSCNPAIGGIGKSHLVKEIDALGGAMAIATDKAGIQFRVLNASKGPAVRATRAQADRTLYKAAIREILESQPNLSLFQQGVDDLLIEDGKVRGVITQMGVLIRANQVVLTAGTFLGGKIHIGLESSSGGRAGDQPSIALADRLRSLPFRVNRLKTGTPPRIDSRSVDFSVMQQQAGDMPLPVMSYLGTADDHPEQVNCHITSTNEECHDIIRGGLDRSPMYTGVIEGTGPRYCPSIEDKVMRFADKNSHQIFVEPEGLTTNELYPNGISTSLPFDVQVEMVRKIKGFENALITRPGYAIEYDFFDPRDLNYSLETKFVKGLYFAGQINGTTGYEEAAAQGLLAGLNAGLAARGKDSWCPRRDQAYLGVLVDDLISLGTNEPYRMFTSRAEYRLTLREDNADQRLTPTGRELGLVNDVRWNFYCDKQAHIQHRLTWLKKTWLQPNTKESAQVDTFLEKPLSREYSLADLLARPRVTYEGLSGALEGSDKALSAYSVDTPIDGLTGLLSEALQTELLRQVDEQVSIHIKYQGYIDRQQDEIEKLKRH

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue589

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LIBB01000009
EMBL· GenBank· DDBJ
KRO73329.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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