A0A0R0K737 · A0A0R0K737_SOYBN
- Protein6-phosphogluconate dehydrogenase, decarboxylating
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids479 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.
Catalytic activity
- 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH
Pathway
Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 92 | substrate; ligand shared between dimeric partners; in other chain | ||||
Sequence: N | ||||||
Binding site | 118-120 | substrate; ligand shared between dimeric partners; in other chain | ||||
Sequence: SGG | ||||||
Active site | 172 | Proton acceptor | ||||
Sequence: K | ||||||
Binding site | 175-176 | substrate; ligand shared between dimeric partners; in other chain | ||||
Sequence: HN | ||||||
Active site | 179 | Proton donor | ||||
Sequence: E | ||||||
Binding site | 180 | substrate; ligand shared between dimeric partners; in other chain | ||||
Sequence: Y | ||||||
Binding site | 250 | substrate; ligand shared between dimeric partners; in other chain | ||||
Sequence: K | ||||||
Binding site | 277 | substrate; ligand shared between dimeric partners; in other chain | ||||
Sequence: R | ||||||
Binding site | 443 | substrate; ligand shared between dimeric partners | ||||
Sequence: R | ||||||
Binding site | 449 | substrate; ligand shared between dimeric partners | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | NADP binding | |
Molecular Function | phosphogluconate 2-dehydrogenase activity | |
Molecular Function | phosphogluconate dehydrogenase (decarboxylating) activity | |
Biological Process | D-gluconate catabolic process | |
Biological Process | pentose-phosphate shunt, oxidative branch |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name6-phosphogluconate dehydrogenase, decarboxylating
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > indigoferoid/millettioid clade > Phaseoleae > Glycine > Glycine subgen. Soja
Accessions
- Primary accessionA0A0R0K737
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 168-465 | 6-phosphogluconate dehydrogenase C-terminal | ||||
Sequence: GNFVKMVHNGIEYGDMQLISEAYDVLKHVGGLSNSELAEIFVEWNRGELESFLIEITADIFKVKDEDGEGFLVDKILDKTGMKGTGKWTVQQAAELSIAAPTIAASLDCRYLSGLKEERESAAAVLKEAGLSDELGRVNVSGVDKKRLIDDVRQALYASKICSYAQGMNLLRAKSNEKGWNLNLGELARIWKGGCIIRAVFLDRIKKAYQRNPNLASLIVDPEFAREMVQRQAAWRRVVGLAVSAGISTPGMCASLAYFDTYRRARLPANLVQAQRDLFGAHTYERVDRPGAFHTEWT |
Sequence similarities
Belongs to the 6-phosphogluconate dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length479
- Mass (Da)52,266
- Last updated2016-01-20 v1
- ChecksumBADA6D29F91B7A58
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM000838 EMBL· GenBank· DDBJ | KRH60004.1 EMBL· GenBank· DDBJ | Genomic DNA |