A0A0Q9XGI6 · A0A0Q9XGI6_DROMO

Function

Catalytic activity

  • 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+ = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.20 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.76 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + hexadecanoyl-CoA = all-trans-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecan-1-ol + hexadecanoyl-CoA = hexadecanyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism; glycerolipid metabolism.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site497

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functiondiacylglycerol O-acyltransferase activity
Molecular Functionretinol O-fatty-acyltransferase activity
Biological Processnegative regulation of lipid storage
Biological Processregulation of nurse cell apoptotic process
Biological Processtriglyceride biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-acyltransferase

Gene names

    • Name
      Dmoj\GI14192
    • ORF names
      Dmoj_GI14192

Organism names

  • Taxonomic identifier
  • Strain
    • Tucson 15081-1352.22
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila

Accessions

  • Primary accession
    A0A0Q9XGI6

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane138-164Helical
Transmembrane198-215Helical
Transmembrane227-248Helical
Transmembrane254-275Helical
Transmembrane364-383Helical
Transmembrane414-438Helical
Transmembrane485-502Helical
Transmembrane508-528Helical
Transmembrane540-558Helical

Keywords

Interaction

Subunit

Homodimer or homotetramer; both forms have similar enzymatic activities.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region13-43Disordered
Compositional bias23-37Polar residues
Region87-127Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    576
  • Mass (Da)
    66,739
  • Last updated
    2016-01-20 v1
  • Checksum
    36E6CD87610B60A8
MYLVDSRAAIDNARAMTATKDPKDQVPKTTTQPAQKNGAAGGLMKRLRRSASVTEHNLNNLRNRNSTQHLFDQHGNPIDLRQYRKVLDKDENGNGTSEKKLRYRRTQSVTRAEEISNKEAKLRKAQPDRSIHRPRDSLFSWSSGFTNFTGLVNWGFLLLCIGGLRLGLENLIKYGIRINPIDWYFFVSGRDQGEGHNALFLVLYSFVHISLCLAVEKGLALEIISEGLGMVIQIANIIFSVLLPVVIIHLKGSAFSIMGATSVCFYYSVLFLKLWSYVQTNMWCRKTYYQRQPRERRPSITVAELKRKHSTGGEDDEDVAKLVQYPENLCYKDIMYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVLIGVNVLMALFQQWIIPSVRNSLIPFSNMDMALATERLLKLALPNHLVWLIFFYLLFHSFLNAIGEVLYFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLYIPVVQMGYSSRQASTIVFLFSAFFHEYLVSVPLQTYKIWAFLGMMGQIPLSAISRYVERRLGPRMGNIIVWASIILGQPLCIMAYYHDYVITHYQNALNGTEHR

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0Q9X3X5A0A0Q9X3X5_DROMODmoj\GI14192583
B4KJR3B4KJR3_DROMODmoj\GI14192561
A0A0Q9XBA3A0A0Q9XBA3_DROMODmoj\GI14192373

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias23-37Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH933807
EMBL· GenBank· DDBJ
KRG02728.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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