A0A0Q7ASS2 · A0A0Q7ASS2_9ACTN
- ProteinArgininosuccinate synthase
- GeneargG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids478 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-citrulline + L-aspartate + ATP = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 17-25 | ATP (UniProtKB | ChEBI) | |||
Binding site | 43 | ATP (UniProtKB | ChEBI) | |||
Binding site | 99 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 129 | ATP (UniProtKB | ChEBI) | |||
Binding site | 131 | ATP (UniProtKB | ChEBI) | |||
Binding site | 131 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 135 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 135 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 136 | ATP (UniProtKB | ChEBI) | |||
Binding site | 136 | L-aspartate (UniProtKB | ChEBI) | |||
Binding site | 139 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 192 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 194 | ATP (UniProtKB | ChEBI) | |||
Binding site | 201 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 203 | L-citrulline (UniProtKB | ChEBI) | |||
Binding site | 280 | L-citrulline (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | argininosuccinate synthase activity | |
Molecular Function | ATP binding | |
Molecular Function | protein homodimerization activity | |
Biological Process | arginine biosynthetic process | |
Biological Process | argininosuccinate metabolic process | |
Biological Process | urea cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameArgininosuccinate synthase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Nocardioidaceae > Nocardioides
Accessions
- Primary accessionA0A0Q7ASS2
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 14-161 | Arginosuccinate synthase-like N-terminal | |||
Domain | 191-404 | Arginosuccinate synthase C-terminal | |||
Sequence similarities
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length478
- Mass (Da)53,023
- Last updated2016-01-20 v1
- Checksum6494DA8CC583470B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LMDV01000014 EMBL· GenBank· DDBJ | KQW43126.1 EMBL· GenBank· DDBJ | Genomic DNA |