A0A0Q4Y6R8 · A0A0Q4Y6R8_9BURK
- ProteinDNA ligase (ATP)
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1133 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Probably binds two magnesium or manganese ions per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 34 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 106 | ||||
Active site | 147 | Proton donor/acceptor | |||
Binding site | 147 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 149 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 149 | Transition state stabilizer | |||
Site | 218 | Important for catalytic activity | |||
Binding site | 245 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 246 | Proton acceptor | |||
Binding site | 246 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 246 | Interaction with DNA substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA ligase (ATP) activity | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | |
Molecular Function | endonuclease activity | |
Molecular Function | metal ion binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA ligase (ATP)
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae
Accessions
- Primary accessionA0A0Q4Y6R8
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 257-280 | Disordered | |||
Domain | 605-747 | ATP-dependent DNA ligase family profile | |||
Region | 825-844 | Disordered | |||
Sequence similarities
Belongs to the DNA repair enzymes AP/ExoA family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,133
- Mass (Da)125,098
- Last updated2016-01-20 v1
- MD5 Checksum70E005E0B79D6F8175056F20D9E94C4C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LMMV01000021 EMBL· GenBank· DDBJ | KQP15185.1 EMBL· GenBank· DDBJ | Genomic DNA |