A0A0Q3TCG9 · A0A0Q3TCG9_9BACI
- ProteinPyrrole-2-carboxylic acid decarboxylase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids488 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the prenyl-FMN-dependent decarboxylation of pyrrole-2-carboxylate (P2C). Can also catalyze the carboxylation of pyrrole in the presence of elevated concentrations of CO2 or bicarbonate.
Catalytic activity
- pyrrole-2-carboxylate + H+ = 1H-pyrrole + CO2
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 K+ per subunit.
Note: Binds 1 Mn2+ per subunit.
Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 165 | K+ (UniProtKB | ChEBI) | |||
Binding site | 169 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 186 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 187 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 187 | prenyl-FMN (UniProtKB | ChEBI) | |||
Binding site | 218 | K+ (UniProtKB | ChEBI) | |||
Binding site | 228 | K+ (UniProtKB | ChEBI) | |||
Binding site | 228 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 228 | prenyl-FMN (UniProtKB | ChEBI) | |||
Active site | 277 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carboxy-lyase activity | |
Molecular Function | metal ion binding | |
Biological Process | cinnamic acid catabolic process | |
Biological Process | ferulate metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyrrole-2-carboxylic acid decarboxylase
- EC number
- Short namesP2C decarboxylase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Heyndrickxia
Accessions
- Primary accessionA0A0Q3TCG9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 12-99 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal | |||
Domain | 115-312 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase-likw Rift-related | |||
Domain | 321-451 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal | |||
Sequence similarities
Belongs to the UbiD family. UbiD-like/FDC subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length488
- Mass (Da)54,570
- Last updated2016-01-20 v1
- ChecksumFB301D271994E2FF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LJJC01000006 EMBL· GenBank· DDBJ | KQL51297.1 EMBL· GenBank· DDBJ | Genomic DNA |