A0A0Q3PK66 · A0A0Q3PK66_AMAAE
- ProteinGlycylpeptide N-tetradecanoyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1553 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
Catalytic activity
- N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H+
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | membrane | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | cyclin-dependent protein serine/threonine kinase inhibitor activity | |
Molecular Function | fatty-acyl-CoA binding | |
Molecular Function | glycylpeptide N-tetradecanoyltransferase activity | |
Molecular Function | protein kinase activity | |
Molecular Function | snRNA binding | |
Biological Process | N-terminal peptidyl-glycine N-myristoylation | |
Biological Process | negative regulation of transcription by RNA polymerase II | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycylpeptide N-tetradecanoyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Psittaciformes > Psittacidae > Amazona
Accessions
- Primary accessionA0A0Q3PK66
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-38 | Basic and acidic residues | ||||
Sequence: MADDSETAARRPPARCARPPAEENDHEYCSDCENETEH | ||||||
Region | 1-83 | Disordered | ||||
Sequence: MADDSETAARRPPARCARPPAEENDHEYCSDCENETEHGSNRGGLSPANDSGVKKKKKKPKRKKEKGDQPSQAQDQPVKVNSL | ||||||
Domain | 530-613 | ACB | ||||
Sequence: FTDFCTSFTTSQGSYRPSYEEMLRFYSYYKQATAGRCEGPRPGFWDPIGRYKWDAWNSLGRMSKEEAMEAYVAEMKKVAQKIID | ||||||
Compositional bias | 642-674 | Basic and acidic residues | ||||
Sequence: PEAFFKRKGEPSKDDPASSLAPEHHKDALPREQ | ||||||
Region | 642-782 | Disordered | ||||
Sequence: PEAFFKRKGEPSKDDPASSLAPEHHKDALPREQQNEQHVPGGALASATTALEGTQVTSDSEGDVYCDTVELMEPEQAGQPLELCLNGGQARPEPLTPPGAGQGEQGEGRRLEGSSSTGLAAPGSKRGLWLARGKEDTESTP | ||||||
Compositional bias | 689-703 | Polar residues | ||||
Sequence: TTALEGTQVTSDSEG | ||||||
Region | 821-948 | Disordered | ||||
Sequence: TSSQGDTAETEPSQLLALQMCIEPEPSCEPELRPEPQRGGAGDGEAERLPPPGAEEVAAGGAEGLPPAAGGAARPGLGPRYRAAVGRAEEWPVKKKHRRRPSKKKRRWKPYSKLSWEEKQQFDERQSL | ||||||
Compositional bias | 848-862 | Basic and acidic residues | ||||
Sequence: CEPELRPEPQRGGAG | ||||||
Compositional bias | 913-930 | Basic residues | ||||
Sequence: VKKKHRRRPSKKKRRWKP | ||||||
Compositional bias | 931-948 | Basic and acidic residues | ||||
Sequence: YSKLSWEEKQQFDERQSL | ||||||
Region | 968-1028 | Disordered | ||||
Sequence: NTTQFLMEDHDQEEPDLKTGLYPRRAAAKSDDTSEEDFLEEGADEDGGSDGMGGDGSEFLQ | ||||||
Compositional bias | 1001-1015 | Acidic residues | ||||
Sequence: SEEDFLEEGADEDGG | ||||||
Coiled coil | 1048-1075 | |||||
Sequence: KQELVKEYLELEKCLSRMEEENNRLRME | ||||||
Domain | 1188-1443 | Protein kinase | ||||
Sequence: YTQLEKLGEGKFGMVFRLQEKATGKIRAGKYFRTQTAKQKQAARDEVELMNLLHHPRLVQCLAAFQGPAELVMVMEYVAGGELFERIVDDDFEHTEPSSTQYLRQILEGLQFMHGQAIVHLDLKPENIVCVSPSSHWLKIIDFGLARKLAPDTPVKVLHGTPEFMAPEVVAFEPVGFSTDMWSVGVICYILLSGESPFQGDNDMETLSNITAAQWDFEEETFLEISQLAKDFISQLLQKDPQRRLSSAGALMHPWL | ||||||
Region | 1495-1553 | Disordered | ||||
Sequence: SQDEEDLGCSPEDQTSGSQLQRGSSVSELLRDKKEEEDVSAAATGEGESSVSVAMPPQT | ||||||
Compositional bias | 1505-1520 | Polar residues | ||||
Sequence: PEDQTSGSQLQRGSSV | ||||||
Compositional bias | 1521-1535 | Basic and acidic residues | ||||
Sequence: SELLRDKKEEEDVSA | ||||||
Compositional bias | 1539-1553 | Polar residues | ||||
Sequence: GEGESSVSVAMPPQT |
Sequence similarities
Belongs to the HEXIM family.
Belongs to the NMT family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,553
- Mass (Da)175,180
- Last updated2016-01-20 v1
- Checksum01F976350BD9F240
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-38 | Basic and acidic residues | ||||
Sequence: MADDSETAARRPPARCARPPAEENDHEYCSDCENETEH | ||||||
Compositional bias | 642-674 | Basic and acidic residues | ||||
Sequence: PEAFFKRKGEPSKDDPASSLAPEHHKDALPREQ | ||||||
Compositional bias | 689-703 | Polar residues | ||||
Sequence: TTALEGTQVTSDSEG | ||||||
Compositional bias | 848-862 | Basic and acidic residues | ||||
Sequence: CEPELRPEPQRGGAG | ||||||
Compositional bias | 913-930 | Basic residues | ||||
Sequence: VKKKHRRRPSKKKRRWKP | ||||||
Compositional bias | 931-948 | Basic and acidic residues | ||||
Sequence: YSKLSWEEKQQFDERQSL | ||||||
Compositional bias | 1001-1015 | Acidic residues | ||||
Sequence: SEEDFLEEGADEDGG | ||||||
Compositional bias | 1505-1520 | Polar residues | ||||
Sequence: PEDQTSGSQLQRGSSV | ||||||
Compositional bias | 1521-1535 | Basic and acidic residues | ||||
Sequence: SELLRDKKEEEDVSA | ||||||
Compositional bias | 1539-1553 | Polar residues | ||||
Sequence: GEGESSVSVAMPPQT |
Keywords
- Technical term