A0A0P7GQZ6 · A0A0P7GQZ6_9EURY

  • Protein
    3-isopropylmalate dehydratase
  • Gene
    hacA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Pathway

Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.

GO annotations

AspectTerm
Molecular Function3-isopropylmalate dehydratase activity
Molecular Functionhomoaconitate hydratase activity
Molecular Functioniron-sulfur cluster binding
Molecular Functionmetal ion binding
Biological ProcessL-leucine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-isopropylmalate dehydratase
  • EC number

Gene names

    • Name
      hacA
    • ORF names
      SY89_01868

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CDK2
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae

Accessions

  • Primary accession
    A0A0P7GQZ6

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-259Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    275
  • Mass (Da)
    29,363
  • Last updated
    2016-01-20 v1
  • Checksum
    9D543D708389A3F2
MYEYGGPAVESLSMPGRMTLCNMSIEGGARAGYVNPDETTYDWLRDTDAFEDDAEQFAERRQYWESIRSGEDATYDDVVTIDADAIEPTVTWGTTPGHTVGVSEPVPAPEDLPPADRAVAERAQEHMGVEPGEPMAGFPVDVAFLGSCTNARLPDLRAAAEIVEGREVADGVRGLVVPGSQRVKAAAEREGLDAVFHDGGFEWRDAGCSMCLGMNDDQLEGDEVCAASSNRNFVGRQGSADGRTILMSPEMVAAAAVTGEVTDVRNLAATPEVAR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LGUC01000001
EMBL· GenBank· DDBJ
KPN31125.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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