A0A0P7GQZ6 · A0A0P7GQZ6_9EURY
- Protein3-isopropylmalate dehydratase
- GenehacA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids275 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Catalytic activity
- (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate
Cofactor
Pathway
Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-isopropylmalate dehydratase activity | |
Molecular Function | homoaconitate hydratase activity | |
Molecular Function | iron-sulfur cluster binding | |
Molecular Function | metal ion binding | |
Biological Process | L-leucine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-isopropylmalate dehydratase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloferacaceae
Accessions
- Primary accessionA0A0P7GQZ6
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-259 | Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha | ||||
Sequence: YEYGGPAVESLSMPGRMTLCNMSIEGGARAGYVNPDETTYDWLRDTDAFEDDAEQFAERRQYWESIRSGEDATYDDVVTIDADAIEPTVTWGTTPGHTVGVSEPVPAPEDLPPADRAVAERAQEHMGVEPGEPMAGFPVDVAFLGSCTNARLPDLRAAAEIVEGREVADGVRGLVVPGSQRVKAAAEREGLDAVFHDGGFEWRDAGCSMCLGMNDDQLEGDEVCAASSNRNFVGRQGSADGRTILMSPEMVAAAAVTG |
Family and domain databases
Sequence
- Sequence statusComplete
- Length275
- Mass (Da)29,363
- Last updated2016-01-20 v1
- Checksum9D543D708389A3F2
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LGUC01000001 EMBL· GenBank· DDBJ | KPN31125.1 EMBL· GenBank· DDBJ | Genomic DNA |