A0A0P6K3B4 · A0A0P6K3B4_HETGA
- Proteinphospholipase A2
- GenePLA2G6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids752 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+This reaction proceeds in the forward direction.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 465 | Nucleophile | |||
Active site | 598 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | calcium-independent phospholipase A2 activity | |
Biological Process | cardiolipin acyl-chain remodeling | |
Biological Process | lipid catabolic process | |
Biological Process | positive regulation of ceramide biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namephospholipase A2
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Hystricomorpha > Bathyergidae > Heterocephalus
Accessions
- Primary accessionA0A0P6K3B4
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for repeat, domain, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Repeat | 151-184 | ANK | |||
Repeat | 219-251 | ANK | |||
Repeat | 316-348 | ANK | |||
Repeat | 349-381 | ANK | |||
Domain | 427-611 | PNPLA | |||
Motif | 431-436 | GXGXXG | |||
Motif | 463-467 | GXSXG | |||
Motif | 598-600 | DGA/G | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length752
- Mass (Da)83,572
- Last updated2016-01-20 v1
- Checksum123A1390E17B007F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GEBF01004564 EMBL· GenBank· DDBJ | JAN99068.1 EMBL· GenBank· DDBJ | Transcribed RNA |