A0A0P0X507 · A0A0P0X507_ORYSJ

Function

function

Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site22ATP (UniProtKB | ChEBI)
Binding site24ATP (UniProtKB | ChEBI)
Binding site25ATP (UniProtKB | ChEBI)
Binding site26ATP (UniProtKB | ChEBI)
Binding site27ATP (UniProtKB | ChEBI)
Binding site118ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionadenylate kinase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Biological Processdevelopmental vegetative growth
Biological Processphosphorylation
Biological Processribosomal small subunit biogenesis
Biological ProcessrRNA processing
Biological Processunidimensional cell growth

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenylate kinase isoenzyme 6 homolog
  • EC number
  • Short names
    AK6
  • Alternative names
    • Dual activity adenylate kinase/ATPase
      (AK/ATPase
      )

Gene names

    • Name
      P0710F09.137
    • ORF names
      OsJ_23948
    • Ordered locus names
      Os07g0412400

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    A0A0P0X507

Proteomes

Genome annotation databases

Subcellular Location

Keywords

Interaction

Subunit

Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.

Structure

3D structure databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region42-65NMPbind
Region117-127LID

Sequence similarities

Belongs to the adenylate kinase family. AK6 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    180
  • Mass (Da)
    20,453
  • Last updated
    2022-01-19 v1
  • Checksum
    A7F41627D180DBB6
MASRGGGARRTRPNVLVTGTPGTGKTTTCSLLADAVDLRHINIGDLVREKSLHDGWDEELECHIINEDLVCDELEDVMEEGGILVDYHGCDFFPERWFDLVVVLQTDNSILHDRLTSRGYMGAKLTNNIECEIFQMLLEEARESYKEEIVMPLRSDNVEDISRNVGTLTEWINNWRPSRS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP005325
EMBL· GenBank· DDBJ
BAC84255.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008213
EMBL· GenBank· DDBJ
BAF21365.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000144
EMBL· GenBank· DDBJ
EEE67018.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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