A0A0P0VDT2 · A0A0P0VDT2_ORYSJ

Function

function

E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.27 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular ComponentRQC complex
Molecular Functionribosomal large subunit binding
Molecular Functionubiquitin protein ligase activity
Molecular Functionzinc ion binding
Biological Processprotein ubiquitination
Biological Processrescue of stalled ribosome
Biological Processribosome-associated ubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    E3 ubiquitin-protein ligase listerin
  • EC number
  • Alternative names
    • RING-type E3 ubiquitin transferase listerin

Gene names

    • Name
      P0020E09.22-1
    • Ordered locus names
      Os01g0977600

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    A0A0P0VDT2

Proteomes

Genome annotation databases

Subcellular Location

Keywords

Interaction

Subunit

Component of the ribosome quality control complex (RQC).

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1871-1918RING-type

Sequence similarities

Belongs to the LTN1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,921
  • Mass (Da)
    215,632
  • Last updated
    2020-02-26 v1
  • Checksum
    91581B8B247D5788
MGKHKGRAASSGLAASLLPHAQGAVPIVGFGGYHGASRVEPAAPSSSTDPDASILLPPDVDSEVLQHLRRLGRKDPTTKLKALSTLSMLFAQKPGQEVVQIVPQWAFEYKRLLLDYNREVRRATHDTMSSLVKTVKKGLAPHLKALMGPWWFSQFDPALEVAQAARHSFEAAFPQSDKRLDALMLCVKETFLHLNENLKLTTQALSDKATPMDELEDMHQRVISSSLLAMATLIDILLGVKLQNCVRDNSSSENTSLSKVLSGTLSSAESAFSMNKYFLDFLKSKSAIIRSATYSLLASYIKHVSHVFNEEAMKVLSPALLGAFNEKDPSCHSSMWDAFLAFSRRFPEAWSYCNIHKVVFSRFWHFLQNGCYGSKQASYPLLVQFLESIPSKAVTTEQFVFDFLHNLWAGRNQRQLSAADSLAFFTTFKQSFLWLLKVLPRHSGGGSSDDIPIKLITYFLAKVVWHDYLRIPSSKNQDISLSGLSDEAISGDCQLSHKESLLASSTRYPTYYLQDLGKCIIEILDEISAMENHLLNIACETLLKDCLDIIHQRESLPNFQYHVEQVVSFFISLDQLIVQKGKTWPLESLARPLIEQSVPAIKSMDTPIVVKLLSVLVEIFRPVPLFLKNSQKESEESVQGYLDVFNGDFVPWCLDRKYSTCSSKIDLLLSLIIDECFFDQWCTIIKYTSAKQKHPVDNKNSHVDDQFELLTLILQKVRERIAGGKLRNLQKNGSLPEHWRHDLLDSAAESVFCDLPATDSHVHYVCAALGGSDQDDQICFLSADTVHKMLGSILKCLTSVLMTSTFEWARFAYVVLLPTEPKDSKVIGAQSFSSNIKMAHFAFKVLEGSLFALRRLEEDSLFPSVLAALFIIEWEYSMALTLDEEHDLKGYKEDIDVGSSACNSSDDHLDEGIHLKANLAESIHTFCQSLSPSFWSDLHPFTLNNLLNILAQSVRCALFQTLELPTESTSVLCSEWMVNMLKLISLDHTKLQSFFYLLLSEGEYWPLWVKPSLQNENAPVKIKFEPVITNETGLKHHQFVAFVDKLVLNLGFGEVILGVPGNTCYNTSQSIDTTSTVPSLSRAWVAAEILCTWKWKGGSVFSTFLPSMIQHLKMESCAEVSILSILLDTLLEGAFHECNQWVLFNAWHISDNEIEKIQDHFLRALVALLFSINSINECIWRESEALVFFEKLLSNLFIGSTVNRKCVKTLPFVMSTIIKPLSGKLKLNEASCYTDLVGQNILSWLDVAISCLSSSPREVLQQDIVDWMQVVLSCFPLNITCGTQKLEVKIEREISDTERSLLLTLFQKYKIFCAIEAPSLSTSGTTLSTMVELLGVKLIAVMVGYCWTELQENDLHFVFHTVQKWIESAVLLVEEMTDAINDAVINQKSNEDTLEKLKLVVSSIDELTLSFGEFALVTLCHLNHLVDIQETENFQSLQIIKSGDFADRNNNMMESMLRLFLASGVSEAIAKSSCEEASSIIASSRVAYMHFWELVASFVIYASPQTRRCALESMELWGLAKGSVSGLYSILFSSQPISHLQFAAYSLLLSEPLCQFSLIKECSLGSNRPLTQESCMGQSIELMPDSEKTLDLREELSSLIEMPTSELLQTDLLAHDRVDAFIAWSLLLSHLQLLPPASITRERVLQYIQDKISPCILDCIFQHIPLRTGAPCGKKKDAELMPEAEVAAQASKNAIITCSLLPCIESLWPVGTWQMASLAGGLYGMMIRLLPSYVRTWFTSLRDRSLSSSIESFTRAWCSPPLLLDEFSQVKDSLYADDNFSVSVNRSAYEIVATYKKEETGIDLVIRLPSCYPLRHVDVECTRSLGISEVKCRKWLLSLTAFVRNQNGAIAEAIHTWKSNFDKEFEGVEECPICYSILHTSNHSLPRLACKTCRHKFHGACLYKWFSTSNKSTCPLCQTPF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP003228
EMBL· GenBank· DDBJ
BAD87044.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008207
EMBL· GenBank· DDBJ
BAF07489.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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