A0A0P0HTG3 · A0A0P0HTG3_9PICO
- ProteinGenome polyprotein
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids978 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Lies on the inner surface of the capsid shell. After binding to the host receptor, the capsid undergoes conformational changes. Capsid protein VP4 is released, capsid protein VP1 N-terminus is externalized, and together, they shape a pore in the host membrane through which the viral genome is translocated into the host cell cytoplasm. After genome has been released, the channel shrinks.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | host cell cytoplasm | |
Cellular Component | T=pseudo3 icosahedral viral capsid | |
Molecular Function | structural molecule activity | |
Biological Process | symbiont entry into host cell | |
Biological Process | virion attachment to host cell |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameGenome polyprotein
Organism names
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Pisuviricota > Pisoniviricetes > Picornavirales > Picornaviridae > Caphthovirinae > Aphthovirus > Foot-and-mouth disease virus
Accessions
- Primary accessionA0A0P0HTG3
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-20 | Disordered | |||
Domain | 1-84 | Capsid protein VP4 Picornavirus | |||
Region | 36-65 | Disordered | |||
Domain | 110-273 | Picornavirus capsid | |||
Domain | 366-489 | Picornavirus capsid | |||
Region | 516-552 | Disordered | |||
Compositional bias | 520-535 | Polar residues | |||
Sequence similarities
Belongs to the picornaviruses polyprotein family.
Family and domain databases
Sequence
- Sequence statusFragment
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length978
- Mass (Da)107,749
- Last updated2016-01-20 v1
- MD5 ChecksumF97715A71A8A967FF0C0B955EC0366FF
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Compositional bias | 520-535 | Polar residues | |||
Non-terminal residue | 978 | ||||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KR108954 EMBL· GenBank· DDBJ | ALJ79265.1 EMBL· GenBank· DDBJ | Viral cRNA |