A0A0N9VMG6 · A0A0N9VMG6_PSEFL
- ProteinSignal recognition particle receptor FtsY
- GeneftsY
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids518 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 319-326 | GTP (UniProtKB | ChEBI) | |||
Binding site | 401-405 | GTP (UniProtKB | ChEBI) | |||
Binding site | 465-468 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | signal recognition particle binding | |
Biological Process | SRP-dependent cotranslational protein targeting to membrane |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSignal recognition particle receptor FtsY
- EC number
- Short namesSRP receptor
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A0N9VMG6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-39 | Disordered | |||
Domain | 486-499 | SRP54-type proteins GTP-binding | |||
Sequence similarities
Belongs to the GTP-binding SRP family. FtsY subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length518
- Mass (Da)54,697
- Last updated2016-01-20 v1
- MD5 Checksum56D31260F53EF5951A1C271027499F5C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP012830 EMBL· GenBank· DDBJ | ALI01047.1 EMBL· GenBank· DDBJ | Genomic DNA |