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A0A0N9VMG6 · A0A0N9VMG6_PSEFL

  • Protein
    Signal recognition particle receptor FtsY
  • Gene
    ftsY
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.

Catalytic activity

Features

Showing features for binding site.

151850100150200250300350400450500
TypeIDPosition(s)Description
Binding site319-326GTP (UniProtKB | ChEBI)
Binding site401-405GTP (UniProtKB | ChEBI)
Binding site465-468GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular FunctionATP hydrolysis activity
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionsignal recognition particle binding
Biological ProcessSRP-dependent cotranslational protein targeting to membrane

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Signal recognition particle receptor FtsY
  • EC number
  • Short names
    SRP receptor

Gene names

    • Name
      ftsY
    • ORF names
      AO353_08250

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • FW300-N2E3
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A0N9VMG6

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cytoplasm

Keywords

Interaction

Subunit

Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-39Disordered
Domain486-499SRP54-type proteins GTP-binding

Sequence similarities

Belongs to the GTP-binding SRP family. FtsY subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    518
  • Mass (Da)
    54,697
  • Last updated
    2016-01-20 v1
  • MD5 Checksum
    56D31260F53EF5951A1C271027499F5C
MFGSNDDKKTPAAAGEKKSLFGWLRKKPQAPAVEQPQPLPEVAPEPVIEAAPVAQAPAAAVLPIAEPVVQPVVEPAPVAEVPRAPEVVHKPWLTLPVAEEPVALVENELAPHITPPIPAPTVVQQAVELLVVEPVPVIDPTAEQLIVDEPDLPQPVIAAFVAPERAPEPVPAPVPAPVVAAPVTAPAPVAPVAAPAPVAAEPVRTEETKAGFFARLKQGLSKTSASIGEGMASLFLGKKIIDDELLEDIETRLLTADVGVEATSVIIQSLTQKVARKQLADADALYKSLQAELANMLKPVEQPLKITSQNKPFVILVVGVNGAGKTTTIGKLAKKLQLEGKKVMLAAGDTFRAAAVEQLQVWGERNKIPVIAQHTGADSASVIFDAVQAAKARGIDVLIADTAGRLHTKDNLMEELKKVRRVISKLDADAPHEVLLVLDAGTGQNAISQAKQFNQTVELTGLALTKLDGTAKGGVIFALAKQFGLPIRYIGVGEGIDDLRTFEAEPFVQALFAERERS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP012830
EMBL· GenBank· DDBJ
ALI01047.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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