A0A0N9HMW6 · A0A0N9HMW6_GEOKU

Function

function

Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site13-23ATP (UniProtKB | ChEBI)
Binding site189Zn2+ (UniProtKB | ChEBI)
Binding site198Zn2+ (UniProtKB | ChEBI)
Binding site201Zn2+ (UniProtKB | ChEBI)
Binding site204Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionligase activity, forming carbon-nitrogen bonds
Molecular Functionzinc ion binding
Biological Processqueuosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    7-cyano-7-deazaguanine synthase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine synthase
    • PreQ(0) synthase
    • Queuosine biosynthesis protein QueC

Gene names

    • Name
      queC

Organism names

Accessions

  • Primary accession
    A0A0N9HMW6

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the QueC family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    224
  • Mass (Da)
    25,149
  • Last updated
    2016-01-20 v1
  • Checksum
    7A5D590DCF7177D1
MMKMNEEKAVVVFSGGQDSTTCLFWAKKQFGEVEAVTFDYGQRHRREIDVAQAIADELGVRHTVLDLSLLGQLAPNALTRRDIAIEQKKGELPTTFVDGRNLLFLSFAAVFAKQRGARHIVTGVCETDFSGYPDCRDVFIKSLNVTLNLAMDYEFVIHTPLMWLTKAETWKLADELGALEFIRTKTLTCYNGIIADGCGECPACALRKRGLDDYLREKAEVESR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KT724210
EMBL· GenBank· DDBJ
ALG04359.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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