A0A0N1IPZ2 · A0A0N1IPZ2_PAPMA
- Protein15-hydroxyprostaglandin dehydrogenase [NAD(+)]
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids221 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD+ = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H+ + NADHThis reaction proceeds in the forward direction.
- 14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD+ = 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + H+ + NADHThis reaction proceeds in the forward direction.
- 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + H+ + NADH = (5S,6R,15S)-trihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD+This reaction proceeds in the forward direction.
- NAD+ + prostaglandin A1 = 15-oxo-prostaglandin A1 + H+ + NADHThis reaction proceeds in the forward direction.
- NAD+ + prostaglandin E1 = 15-oxoprostaglandin E1 + H+ + NADHThis reaction proceeds in the forward direction.
- NAD+ + resolvin D1 = 17-oxoresolvin D1 + H+ + NADHThis reaction proceeds in the forward direction.
- NAD+ + resolvin D1 = 8-oxoresolvin D1 + H+ + NADHThis reaction proceeds in the forward direction.
- NAD+ + resolvin D2 = 16-oxoresolvin D2 + H+ + NADHThis reaction proceeds in the forward direction.
- NAD+ + resolvin D2 = 7-oxoresolvin D2 + H+ + NADHThis reaction proceeds in the forward direction.
- NAD+ + resolvin E1 = 18-oxo-resolvin E1 + H+ + NADHThis reaction proceeds in the forward direction.
- lipoxin A4 + NAD+ = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H+ + NADHThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name15-hydroxyprostaglandin dehydrogenase [NAD(+)]
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Lepidoptera > Glossata > Ditrysia > Papilionoidea > Papilionidae > Papilioninae > Papilio
Accessions
- Primary accessionA0A0N1IPZ2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length221
- Mass (Da)24,416
- Last updated2015-12-09 v1
- Checksum97CD916400A76B1A
Keywords
- Technical term