A0A0N1HHL1 · A0A0N1HHL1_9EURO
- ProteinPhosphomannomutase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids266 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Catalytic activity
- alpha-D-mannose 1-phosphate = D-mannose 6-phosphate
Cofactor
Pathway
Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 21 | Proton donor/acceptor | |||
Binding site | 21 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 23 | Proton donor/acceptor | |||
Binding site | 23 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 30 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 136 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 147 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 154 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 192 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 194 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 228 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 240 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 242 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 245 | Mg2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | metal ion binding | |
Molecular Function | phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process | |
Biological Process | mannose metabolic process | |
Biological Process | protein N-linked glycosylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphomannomutase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Phialophora
Accessions
- Primary accessionA0A0N1HHL1
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length266
- Mass (Da)30,043
- Last updated2015-12-09 v1
- Checksum33E9A9B938E9D4A9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LFJN01000001 EMBL· GenBank· DDBJ | KPI46047.1 EMBL· GenBank· DDBJ | Genomic DNA |