A0A0N1HHL1 · A0A0N1HHL1_9EURO

Function

function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site21Proton donor/acceptor
Binding site21Mg2+ 1 (UniProtKB | ChEBI)
Active site23Proton donor/acceptor
Binding site23Mg2+ 1 (UniProtKB | ChEBI)
Binding site30alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site136alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site147alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site154alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site192alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site194alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site228Mg2+ 1 (UniProtKB | ChEBI)
Binding site240Mg2+ 1 (UniProtKB | ChEBI)
Binding site242Mg2+ 1 (UniProtKB | ChEBI)
Binding site245Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmetal ion binding
Molecular Functionphosphomannomutase activity
Biological ProcessGDP-mannose biosynthetic process
Biological Processmannose metabolic process
Biological Processprotein N-linked glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomannomutase
  • EC number

Gene names

    • ORF names
      AB675_645

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CBS 131958
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Phialophora

Accessions

  • Primary accession
    A0A0N1HHL1

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the eukaryotic PMM family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    266
  • Mass (Da)
    30,043
  • Last updated
    2015-12-09 v1
  • Checksum
    33E9A9B938E9D4A9
MAELFSPLEARPLKDTICLFDVDGTLSPARLHASPEMLQTLAALRHKCAIGFVGGSNLPKQEEQLSTPNVPVTSLFDFCFSENGLTAYRLGKPLASQSFIGWIGEEKYQKLVRFLLRYIAGIEGLPAMRGTFVEFRNGMVNVSPVGRNASKEERDEFEKWDKESKCREKMIAAIKEEFPDSGLTFSIGGQISFDVFPTGWDKTYCLQYIEKEKEISGIEYKKIHFFGDKAFEGGNDWEIYNDKRTIGHAVKDPSDTIRILKEEFGV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LFJN01000001
EMBL· GenBank· DDBJ
KPI46047.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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