A0A0N1GX53 · A0A0N1GX53_9EURO

  • Protein
    Methylthioribulose-1-phosphate dehydratase
  • Gene
    MDE1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site100substrate
Binding site117Zn2+ (UniProtKB | ChEBI)
Binding site119Zn2+ (UniProtKB | ChEBI)
Active site146Proton donor/acceptor
Binding site202Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmethylthioribulose 1-phosphate dehydratase activity
Molecular Functionzinc ion binding
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribulose-1-phosphate dehydratase
  • EC number
  • Short names
    MTRu-1-P dehydratase

Gene names

    • Name
      MDE1
    • ORF names
      AB675_11627

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CBS 131958
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Phialophora

Accessions

  • Primary accession
    A0A0N1GX53

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-229Class II aldolase/adducin N-terminal

Sequence similarities

Belongs to the aldolase class II family. MtnB subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    240
  • Mass (Da)
    26,817
  • Last updated
    2015-12-09 v1
  • Checksum
    2C66F554D730F5EF
MGSIEEVRPGDELVISADPNHPANLIPRLCKQFYTLGWVTGTGGGASIKQGDHVYIAPSGVQKELMEPENIFVMSWPTPKYPPSERVYIRKPLDLKPSACTPLFLSAFEQGAGCCIHTHSQWAVLVTLLVEQKFSKDACFEISTIEQIKGIPAGKGKGMLGYHDKLKIPIIENTPFEEDLTGSLEKAMQQYPDTYAVLVRRHGIYVWGDTWIKAKTQCESLDYLFQLAVEMHKLGLPWLP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LFJN01000054
EMBL· GenBank· DDBJ
KPI34626.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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