A0A0N0KZW1 · A0A0N0KZW1_9MICO
- ProteinIsopentenyl-diphosphate Delta-isomerase
- Geneidi
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids189 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Catalytic activity
- isopentenyl diphosphate = dimethylallyl diphosphate
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Mg2+ ion per subunit. The magnesium ion binds only when substrate is bound.
Note: Binds 1 Mn2+ ion per subunit.
Pathway
Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 43 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 50 | Mn2+ (UniProtKB | ChEBI) | |||
Active site | 85 | ||||
Binding site | 87 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 105 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 132 | Mn2+ (UniProtKB | ChEBI) | |||
Active site | 134 | ||||
Binding site | 134 | Mn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | isopentenyl-diphosphate delta-isomerase activity | |
Molecular Function | metal ion binding | |
Biological Process | dimethylallyl diphosphate biosynthetic process | |
Biological Process | isoprenoid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameIsopentenyl-diphosphate Delta-isomerase
- EC number
- Short namesIPP isomerase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Frigoribacterium
Accessions
- Primary accessionA0A0N0KZW1
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length189
- Mass (Da)20,522
- Last updated2015-12-09 v1
- Checksum4DD5611C901C2381
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LHOZ01000061 EMBL· GenBank· DDBJ | KPG84728.1 EMBL· GenBank· DDBJ | Genomic DNA |