A0A0N0KZW1 · A0A0N0KZW1_9MICO

Function

function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit. The magnesium ion binds only when substrate is bound.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site43Mn2+ (UniProtKB | ChEBI)
Binding site50Mn2+ (UniProtKB | ChEBI)
Active site85
Binding site87Mn2+ (UniProtKB | ChEBI)
Binding site105Mg2+ (UniProtKB | ChEBI)
Binding site132Mn2+ (UniProtKB | ChEBI)
Active site134
Binding site134Mn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmetal ion binding
Biological Processdimethylallyl diphosphate biosynthetic process
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate Delta-isomerase
  • EC number
  • Short names
    IPP isomerase
  • Alternative names
    • IPP:DMAPP isomerase
    • Isopentenyl pyrophosphate isomerase

Gene names

    • Name
      idi
    • ORF names
      AEQ27_06505

Organism names

  • Taxonomic identifier
  • Strain
    • RIT-PI-h
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Frigoribacterium

Accessions

  • Primary accession
    A0A0N0KZW1

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain48-182Nudix hydrolase

Sequence similarities

Belongs to the IPP isomerase type 1 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    189
  • Mass (Da)
    20,522
  • Last updated
    2015-12-09 v1
  • Checksum
    4DD5611C901C2381
MTREISTHPQPTSGDRPGAHDELVVLLDDEGTPIGTTAKATVHTATTPLHLAFSCHVTDDLGRVLVTRRALSKKTWPGVWTNSFCGHPAPGETPAEALMRRAHQELGMEVRDVEVILPEFRYLATDASGVVENEICPVFTARAVGLPDPSPDEVAEWAWVEPAELRDAVAAAPFAFSPWLGWQLAAWPA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LHOZ01000061
EMBL· GenBank· DDBJ
KPG84728.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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