A0A0M9ES07 · A0A0M9ES07_FUSLA

  • Protein
    Very-long-chain 3-oxoacyl-CoA reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site198substrate
Active site211Proton acceptor

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionketoreductase activity
Molecular Functionvery-long-chain 3-oxoacyl-CoA reductase activity
Biological Processfatty acid elongation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Very-long-chain 3-oxoacyl-CoA reductase
  • EC number
  • Alternative names
    • 3-ketoacyl-CoA reductase
      (3-ketoreductase
      ; KAR
      )
    • Microsomal beta-keto-reductase

Gene names

    • ORF names
      FLAG1_08434

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Fl201059
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium

Accessions

  • Primary accession
    A0A0M9ES07

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass membrane protein

Keywords

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    334
  • Mass (Da)
    36,610
  • Last updated
    2015-12-09 v1
  • Checksum
    D2A6B0FD97022EFE
MTALADFFENVPQPLQWGLAGVGALFLGSKILSYLQLVLSAFVLGGTNLRKYGKPGTWAVITGASDGLGKEYALQLAAKGFNLVLVSRTLSKLETLAAEIQQKYPGKGLQVKVLDMDFSKNNDTDYERLSELIYGLDVGILINNVGQSHSIPVPFLETDKEELQNIIAINCTGTLRVTQTVAPIMKARKNGLILTMGSFGGWTPTALLATYSGSKAFLQQWSNALAAELADDKVDVYLVLSHLVTTAMSKIRRPSLLVPNARNFVKATLGKVGLGGYQTAPYTYTPWWSHSFMLWFIENIPGANGPITMSVNKKMHEDIRRRALRKAAREAKKQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JXCE01000251
EMBL· GenBank· DDBJ
KPA38718.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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