A0A0M7GC82 · A0A0M7GC82_ENTCL

  • Protein
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • Gene
    bioH_1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

126020406080100120140160180200220240260
TypeIDPosition(s)Description
Binding site22substrate
Active site82Nucleophile
Binding site82-83substrate
Binding site143-147substrate
Active site207
Active site235
Binding site235substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarboxylic ester hydrolase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH_1
    • Synonyms
      bioH
    • ORF names
      NCTC10005_01385

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCTC10005
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Enterobacter > Enterobacter cloacae complex

Accessions

  • Primary accession
    A0A0M7GC82

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-242AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    260
  • Mass (Da)
    28,645
  • Last updated
    2015-12-09 v1
  • Checksum
    E0ECC8D805342B4F
MKTLWWQTVGTGNRHLVLLHGWGLNAEVWHCVNEELASHFTLHLVDLPGFGRSCGYGAMSLDEMAQQVLAAAPQQAIWLGWSLGGLVASEVALTNPERVQALVTVASSPNFSAQEEWPGIKPDVLSNFQRQLSEDYQRTVERFLALQTMGTESARKDARLLKQTVLSLPMPDVEVLNGGLELLKTVDLREPLTALAVPHLRIYGYLDGLVPRKVVPLLDELWPESQSLTIAKAAHAPFISHPAEFCSALIAFSHEVPTTP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UGJB01000004
EMBL· GenBank· DDBJ
STQ08699.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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