A0A0M6X1M4 · A0A0M6X1M4_9FIRM

  • Protein
    Polyamine aminopropyltransferase
  • Gene
    speE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site31S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site86spermidine (UniProtKB | ChEBI)
Binding site106S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site137-138S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Active site155Proton acceptor
Binding site155-158spermidine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionspermidine synthase activity
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyamine aminopropyltransferase
  • Alternative names
    • Putrescine aminopropyltransferase
      (PAPT
      )
    • Spermidine synthase
      (SPDS
      ; SPDSY
      ) (EC:2.5.1.16
      ) . EC:2.5.1.16 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      speE
    • ORF names
      GMD30_02430
      , M72_17781

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • M72
    • BIOML-A1
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Roseburia

Accessions

  • Primary accession
    A0A0M6X1M4

Proteomes

Interaction

Subunit

Homodimer or homotetramer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-237PABS

Sequence similarities

Belongs to the spermidine/spermine synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    285
  • Mass (Da)
    33,234
  • Last updated
    2015-12-09 v1
  • Checksum
    4E804BBB0624B13F
MQMWFSEYHTVNVKLDVRIEEQLFSGKSEYQKIDVFKSYEFGKMAALDGEIVFSDADEFIYDEMVTHVPMAVHPNAKKILIIGGGDGGVAKELIKYPFVEKIDVVETDKMFVDVCRKFFPEVACGLEDPRISMYYDDGLRFLRGKNDEYDLIINDSTDPLGHTEGLFTKEFYGSCYKALREDGIMVYQHGSPFYDEDEAECRKMHRKVYKSFPISRVYQAHIPTCPSGYWLFGFASKKYHPLNDLDAERWDALGMKTWYYTTNLHRGAFMLPKYVEDLLEEEETR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CVRR01000082
EMBL· GenBank· DDBJ
CRL42973.1
EMBL· GenBank· DDBJ
Genomic DNA
WNAL01000003
EMBL· GenBank· DDBJ
MTR80583.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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