A0A0M3LRK4 · A0A0M3LRK4_9RODE

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

136950100150200250300350
TypeIDPosition(s)Description
Binding site76Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site90Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site175Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site189Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site194a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CTYB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Gerbillinae > Gerbilliscus

Accessions

  • Primary accession
    A0A0M3LRK4

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane23-45Helical
Transmembrane80-100Helical
Transmembrane106-126Helical
Transmembrane138-159Helical
Transmembrane171-193Helical
Transmembrane222-240Helical
Transmembrane281-301Helical
Transmembrane313-333Helical
Transmembrane339-365Helical

Keywords

Interaction

Subunit

The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-202Cytochrome b/b6 N-terminal region profile
Domain203-369Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    369
  • Mass (Da)
    41,678
  • Last updated
    2015-12-09 v1
  • MD5 Checksum
    9CF12A550A59555C614DB270BEE1E20F
HPLFKIINHSFIDLPTPSNISSWWNFGSLLGLCLIIQITTGLFLAMHYTADTTTAFSSVSHICRDVNYGWLIRYMHANGASMFFICLFIHIGRGIYYGSYLYTETWNVGIILLFSVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTTIVEWIWGGFSVDKPTLTRFFAFHFILPFIIAALAVVHLLFLHETGSNNPMGINSNVDKIPFHPYYTVKDFLGVILLLFSFLLVVLFSPDLLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILILVLLPLTHTSKQRSLMFRPISQFMFWMLVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILIFLPIAGIIENHM

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue369

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM454004
EMBL· GenBank· DDBJ
AJD87392.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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