A0A0M3LIT2 · A0A0M3LIT2_9SALA

Function

Catalytic activity

  • a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H+
    This reaction proceeds in the forward direction.
    EC:2.4.1.152 (UniProtKB | ENZYME | Rhea)
  • a neolactoside nLc4Cer + GDP-beta-L-fucose = a neolactoside III3-alpha-Fuc-nLc4Cer + GDP + H+
    This reaction proceeds in the forward direction.
  • alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose = a neolactoside IV3-alpha-Gal,III3-alpha-Fuc-nLc4Cer + GDP + H+
    This reaction proceeds in the forward direction.
  • alpha-N-glycoloylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP-beta-L-fucose = alpha-N-glycoloylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP + H+
    This reaction proceeds in the forward direction.
  • an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H+
    This reaction proceeds in the forward direction.
  • an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose = an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H+
    This reaction proceeds in the forward direction.
  • an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H+
    This reaction proceeds in the forward direction.
  • beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose = beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H+
    This reaction proceeds in the forward direction.

Pathway

Glycolipid biosynthesis.
Protein modification; protein glycosylation.

GO annotations

AspectTerm
Cellular ComponentGolgi cisterna membrane
Cellular ComponentGolgi membrane
Molecular Functionalpha-(1->3)-fucosyltransferase activity
Biological Processfucosylation
Biological Processlipid metabolic process
Biological Processprotein glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fucosyltransferase
  • EC number

Gene names

    • Name
      FUT9

Organism names

Accessions

  • Primary accession
    A0A0M3LIT2

Subcellular Location

Golgi apparatus, Golgi stack membrane
; Single-pass type II membrane protein
Golgi apparatus, trans-Golgi network membrane
; Single-pass type II membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-88Fucosyltransferase N-terminal

Sequence similarities

Belongs to the glycosyltransferase 10 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    253
  • Mass (Da)
    29,789
  • Last updated
    2015-12-09 v1
  • Checksum
    31CA047EC942A9B3
CDSLFNIHGCHLTIDRSLYNKSHAVLIHHRDINWDLTNLPQQVRPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFMIISTNPFEIEVPSKDKLVCWVVSNWNPDHARVKYYNELSKYIEIQTYGQAFGDYLNDKSLIPTISTCKFYLSFENSIHKDYITEKLYNALLAGSVPVVLGPSRENYENYIPADSFIHVHDFLSPRELADYLLLLNSNNEMYLSLFNWRKYFTVNLSQFWESHA

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue253

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF912799
EMBL· GenBank· DDBJ
AIW47129.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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