A0A0L7KA79 · A0A0L7KA79_PLAFX

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapicoplast
Cellular ComponentRNA polymerase II, core complex
Molecular FunctionDNA binding
Molecular Functionmetal ion binding
Molecular Functionribonucleoside binding
Molecular FunctionRNA polymerase II activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta
  • EC number

Gene names

    • ORF names
      PFHG_02012

Organism names

  • Taxonomic identifier
  • Strain
    • HB3
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)

Accessions

  • Primary accession
    A0A0L7KA79

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain48-461RNA polymerase beta subunit protrusion
Domain218-412RNA polymerase Rpb2
Domain487-551RNA polymerase Rpb2
Domain587-647RNA polymerase Rpb2
Domain674-720RNA polymerase Rpb2
Domain727-912DNA-directed RNA polymerase subunit 2 hybrid-binding
Region918-942Disordered
Region1003-1024Disordered
Domain1024-1244DNA-directed RNA polymerase subunit 2 hybrid-binding
Domain1246-1337RNA polymerase Rpb2

Sequence similarities

Belongs to the RNA polymerase beta chain family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,340
  • Mass (Da)
    151,723
  • Last updated
    2015-11-11 v1
  • Checksum
    62667491EF40AD30
MAVKIEAPYFTNDFVKTEQLSDNDKNPNEQITEDDSWVVIGSFFGSHGLVNQQIESYNDFIEYRMQEIIDEHPKIEIRPQPQYRTDRDENDNIIYSLKFGQLSLDRPFYDEKNLSNKNLWPQEARLRNLTYSSAIYIDIEQSTYIIDEVTKKPVLKEKFIYERINLGRIPLMLKSMFCWTKGLPENEIADMGECSYDQGGYFIVNGGEKVLVAQERMANNFIYVFKKKQPSKFGWVAEIRSQMERSQATSGFSVKMKTRSGGSQYGSNKSGGQLVATLPYIRTEISVGILFRALGCTSDRDILQRIVYDFNDKLMINALRETLEECIEYPTQDVCLDFIGKRGPTVGASREKRILYAKELLRKEVLPHMGTHPGVESKKSYFIGYMINRLLLAELGRIKEDDRDHFGKKRLDIAGPLMASSFSTYFRKMAKDVRRVLQRQIDNNKPFDVAGAIRSCSQITQGMQYQLATGNWGKDKDGKVIRTGVAQVLNRLTYSSCLSHLRRLNTPLGREGKMAKPRQLHNTHWGMICPFETPEGQSVGLVKNLSLMCDISVGTSTNNIYEFLTEWGLESLDEVPPELMKEKVKLFLNGKWVGCFNQIDNLIETLYELRRRCDISPEASIVRDVNSKEIKIFTDSGRAMRPLYVVKNVNGENKLKLTKEHVNNIEKYPETYNWDYLIQEGIIEYIDCEEEETTMISMFIDDLKTGTGYYNNFTHCEIHPSLILGVCASIIPFSDHNQSPRNTYQSAMGKQAMGIYVTNFNIRLDTLAHLLYYPQKPLVCTKVMEYLRFRELPAGINAIVAIMCYTGYNQEDSLIMNQSSIDRGLFRSVFYRTYTSEEKQQGSLIIESFEKPSVRVVKNLKRGDYTKLDDDGLIAPGIRVLGDDIIIGKVSPNIDDEDDIIIEKRNTSSSSIQIYNKDSISNNNSNNSNNNMNNMSNMSNMSNIRSSISSNLSFSSNIGSSNVLDTLPDSPINNTYNNNNNININSSSNNYSLHGAASVTSSTPSSTTIFSSGQTAGSSNSNTKYGTTIVSSTKDDTEIPTLTISSTNVLKQYKKDCSLSLRSNENGVIDTVMLSSNSRGNKFAKVKVRSVRIPQIGDKFASRHGQKGTIGITYRTEDMPFSSLGIFPDIIMNPHAVPSRMTIGHLVECLTGKVAAIEGGEGDATPFSKITVQEISQKLHNLGYEKYGNEMLYNGHNGRMLKSKIFIGPTYYQRLKHMVEDKIHARSRGPLTMITRQPTEGRSRDGGLRFGEMERDCMISHGSAKMLKERLFEESDAYRVHVCDNCGLCCIADINKNAYECTVCNSKTNISQIYLPYACKLLFQELMTMAIYPKLVLEDV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH671955
EMBL· GenBank· DDBJ
KOB60177.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp