A0A0L7KA79 · A0A0L7KA79_PLAFX
- ProteinDNA-directed RNA polymerase subunit beta
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1340 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | apicoplast | |
Cellular Component | RNA polymerase II, core complex | |
Molecular Function | DNA binding | |
Molecular Function | metal ion binding | |
Molecular Function | ribonucleoside binding | |
Molecular Function | RNA polymerase II activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed RNA polymerase subunit beta
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)
Accessions
- Primary accessionA0A0L7KA79
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 48-461 | RNA polymerase beta subunit protrusion | ||||
Sequence: GLVNQQIESYNDFIEYRMQEIIDEHPKIEIRPQPQYRTDRDENDNIIYSLKFGQLSLDRPFYDEKNLSNKNLWPQEARLRNLTYSSAIYIDIEQSTYIIDEVTKKPVLKEKFIYERINLGRIPLMLKSMFCWTKGLPENEIADMGECSYDQGGYFIVNGGEKVLVAQERMANNFIYVFKKKQPSKFGWVAEIRSQMERSQATSGFSVKMKTRSGGSQYGSNKSGGQLVATLPYIRTEISVGILFRALGCTSDRDILQRIVYDFNDKLMINALRETLEECIEYPTQDVCLDFIGKRGPTVGASREKRILYAKELLRKEVLPHMGTHPGVESKKSYFIGYMINRLLLAELGRIKEDDRDHFGKKRLDIAGPLMASSFSTYFRKMAKDVRRVLQRQIDNNKPFDVAGAIRSCSQITQ | ||||||
Domain | 218-412 | RNA polymerase Rpb2 | ||||
Sequence: ANNFIYVFKKKQPSKFGWVAEIRSQMERSQATSGFSVKMKTRSGGSQYGSNKSGGQLVATLPYIRTEISVGILFRALGCTSDRDILQRIVYDFNDKLMINALRETLEECIEYPTQDVCLDFIGKRGPTVGASREKRILYAKELLRKEVLPHMGTHPGVESKKSYFIGYMINRLLLAELGRIKEDDRDHFGKKRLD | ||||||
Domain | 487-551 | RNA polymerase Rpb2 | ||||
Sequence: QVLNRLTYSSCLSHLRRLNTPLGREGKMAKPRQLHNTHWGMICPFETPEGQSVGLVKNLSLMCDI | ||||||
Domain | 587-647 | RNA polymerase Rpb2 | ||||
Sequence: FLNGKWVGCFNQIDNLIETLYELRRRCDISPEASIVRDVNSKEIKIFTDSGRAMRPLYVVK | ||||||
Domain | 674-720 | RNA polymerase Rpb2 | ||||
Sequence: WDYLIQEGIIEYIDCEEEETTMISMFIDDLKTGTGYYNNFTHCEIHP | ||||||
Domain | 727-912 | DNA-directed RNA polymerase subunit 2 hybrid-binding | ||||
Sequence: CASIIPFSDHNQSPRNTYQSAMGKQAMGIYVTNFNIRLDTLAHLLYYPQKPLVCTKVMEYLRFRELPAGINAIVAIMCYTGYNQEDSLIMNQSSIDRGLFRSVFYRTYTSEEKQQGSLIIESFEKPSVRVVKNLKRGDYTKLDDDGLIAPGIRVLGDDIIIGKVSPNIDDEDDIIIEKRNTSSSSI | ||||||
Region | 918-942 | Disordered | ||||
Sequence: DSISNNNSNNSNNNMNNMSNMSNMS | ||||||
Region | 1003-1024 | Disordered | ||||
Sequence: TPSSTTIFSSGQTAGSSNSNTK | ||||||
Domain | 1024-1244 | DNA-directed RNA polymerase subunit 2 hybrid-binding | ||||
Sequence: KYGTTIVSSTKDDTEIPTLTISSTNVLKQYKKDCSLSLRSNENGVIDTVMLSSNSRGNKFAKVKVRSVRIPQIGDKFASRHGQKGTIGITYRTEDMPFSSLGIFPDIIMNPHAVPSRMTIGHLVECLTGKVAAIEGGEGDATPFSKITVQEISQKLHNLGYEKYGNEMLYNGHNGRMLKSKIFIGPTYYQRLKHMVEDKIHARSRGPLTMITRQPTEGRSR | ||||||
Domain | 1246-1337 | RNA polymerase Rpb2 | ||||
Sequence: GGLRFGEMERDCMISHGSAKMLKERLFEESDAYRVHVCDNCGLCCIADINKNAYECTVCNSKTNISQIYLPYACKLLFQELMTMAIYPKLVL |
Sequence similarities
Belongs to the RNA polymerase beta chain family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,340
- Mass (Da)151,723
- Last updated2015-11-11 v1
- Checksum62667491EF40AD30
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH671955 EMBL· GenBank· DDBJ | KOB60177.1 EMBL· GenBank· DDBJ | Genomic DNA |