A0A0L0SMU8 · A0A0L0SMU8_ALLM3
- ProteinATP-dependent (S)-NAD(P)H-hydrate dehydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids353 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Catalytic activity
- (6S)-NADHX + ATP = ADP + phosphate + NADH + H+
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 159 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 212-218 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 247-251 | ATP (UniProtKB | ChEBI) | |||
Binding site | 267-276 | ATP (UniProtKB | ChEBI) | |||
Binding site | 277 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent NAD(P)H-hydrate dehydratase activity | |
Biological Process | metabolite repair | |
Biological Process | nicotinamide nucleotide metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent (S)-NAD(P)H-hydrate dehydratase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Blastocladiomycota > Blastocladiomycetes > Blastocladiales > Blastocladiaceae > Allomyces
Accessions
- Primary accessionA0A0L0SMU8
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-17 | ||||
Chain | PRO_5005548182 | 18-353 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | ||
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length353
- Mass (Da)37,966
- Last updated2015-11-11 v1
- ChecksumB84180B4771CF307
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GG745343 EMBL· GenBank· DDBJ | KNE63807.1 EMBL· GenBank· DDBJ | Genomic DNA |