A0A0L0SMU8 · A0A0L0SMU8_ALLM3

Function

function

Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site159(6S)-NADPHX (UniProtKB | ChEBI)
Binding site212-218(6S)-NADPHX (UniProtKB | ChEBI)
Binding site247-251ATP (UniProtKB | ChEBI)
Binding site267-276ATP (UniProtKB | ChEBI)
Binding site277(6S)-NADPHX (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionATP-dependent NAD(P)H-hydrate dehydratase activity
Biological Processmetabolite repair
Biological Processnicotinamide nucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent (S)-NAD(P)H-hydrate dehydratase
  • EC number
  • Alternative names
    • ATP-dependent NAD(P)HX dehydratase

Gene names

    • ORF names
      AMAG_08878

Organism names

Accessions

  • Primary accession
    A0A0L0SMU8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-17
ChainPRO_500554818218-353ATP-dependent (S)-NAD(P)H-hydrate dehydratase

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain48-349YjeF C-terminal

Sequence similarities

Belongs to the NnrD/CARKD family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    353
  • Mass (Da)
    37,966
  • Last updated
    2015-11-11 v1
  • Checksum
    B84180B4771CF307
MHRVALVSRHLFLAATAANSTFRPAIIRTKPFRTMASSTPAAAKDDALRVFREMIVPRLDPAMHKGQCGRVAVIGGCEEYTGAPFFSAMASLKLGVDLSHVICDANAGTVIKSYSPELIVHPYLRTEDSVAQRPASTPDIVHRVTEQLDRFHAIVIGPGLGRDPLILTLVALLLPEIRARSLPLVLDADALHLVSTRPDLVRGYPRAVLTPNVVEYARLCRALELDPSVATPHEVGETLGGVTVVRKGAVDVVARPGMDEVRVDDQGGLRRFGGQGDVLTGALAAFLAWNELAINAHDGEDRRDRWTVAACAAACTVTRTASRIAYEEHGRGTTTGDVLAVLPRAFIEVVGEV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG745343
EMBL· GenBank· DDBJ
KNE63807.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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