A0A0L0RZD9 · A0A0L0RZD9_ALLM3

Function

function

Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for binding site, active site.

134350100150200250300
TypeIDPosition(s)Description
Binding site207substrate
Active site220Proton acceptor

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionketoreductase activity
Molecular Functionvery-long-chain 3-oxoacyl-CoA reductase activity
Biological Processfatty acid elongation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Very-long-chain 3-oxoacyl-CoA reductase
  • EC number
  • Alternative names
    • 3-ketoacyl-CoA reductase
      (3-ketoreductase
      ; KAR
      )
    • Microsomal beta-keto-reductase

Gene names

    • ORF names
      AMAG_01579

Organism names

Accessions

  • Primary accession
    A0A0L0RZD9

Proteomes

Organism-specific databases

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass membrane protein

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    343
  • Mass (Da)
    36,886
  • Last updated
    2015-11-11 v1
  • Checksum
    133A7AB04962194D
MDYLTNLASCKCIDAYVAAVRSAPLSLLVLGGLGTVVVLKYALDLAKLVFNLTLRGGINIKKFGAGTGAWAVITGASDGIGKEFALQLAQAKYNVVLSARTESKLNTLASEISSKYNVETKVVPFDYSHATSADYEKLGAELAPLKVTILVNNVGTNHEFPVSFVEENPAVIESIVNVNIKSVMAVTRLVAPKMVAQQQGLILNVGSFAGLMPQPLLSVYSASKAYLLTWSQAVGRELAPHKVHVQCLSTYFVVSAMSKIRKSSWTIPTAHEYVRAALRRLGNPGGASTPFTSSPFPAHAIMNWVIDRVGSPSFWVNKAYATQASIRKRALAKKAREAGKKDN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG745329
EMBL· GenBank· DDBJ
KNE55693.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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