A0A0L0RY62 · A0A0L0RY62_ALLM3

Function

function

Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site67Phosphoserine intermediate
Binding site67Mg2+ (UniProtKB | ChEBI); via phosphate group
Binding site275Mg2+ (UniProtKB | ChEBI)
Binding site277Mg2+ (UniProtKB | ChEBI)
Binding site279Mg2+ (UniProtKB | ChEBI)
Binding site369-371substrate
Binding site491-495substrate
Binding site500substrate

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionphosphoacetylglucosamine mutase activity
Biological Processcarbohydrate metabolic process
Biological ProcessUDP-N-acetylglucosamine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoacetylglucosamine mutase
  • EC number
  • Short names
    PAGM
  • Alternative names
    • Acetylglucosamine phosphomutase
    • N-acetylglucosamine-phosphate mutase

Gene names

    • ORF names
      AMAG_00956

Organism names

Accessions

  • Primary accession
    A0A0L0RY62

Proteomes

Organism-specific databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain60-89Alpha-D-phosphohexomutase alpha/beta/alpha
Domain102-174Alpha-D-phosphohexomutase alpha/beta/alpha
Domain191-282Phosphoacetylglucosamine mutase AMG1
Domain296-430Phosphoacetylglucosamine mutase AMG1
Domain464-519Alpha-D-phosphohexomutase C-terminal

Sequence similarities

Belongs to the phosphohexose mutase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    537
  • Mass (Da)
    57,925
  • Last updated
    2015-11-11 v1
  • Checksum
    DE3B844D020FF0EC
MSNVRQAILDASAAHPAPAGVHYTYGTAGFRMNADLLDPVMYRVGLLATLRSKALGGKVIGVMVTASHNPVRDNGVKLVDPMGEMLKQSWEGYATQLANAQTHEEVADLYFSIAQECEIDLDQSASVVVGRDTRPSGEALVASLIDGLTASGAIVTDLGLKTTPQLHFVTRCLNDPSYGTPTEEGYYQKISDAYKTLVAGLEPLKITVDCAHGVGAPKLRDLTTYLGDALDVTVVNGDVEHGILNYHVGADFVKVNVKQPEGFDLAPNGIYCSFDGDADRIVFYYADEAGAFHLLDGDRITALVGAFIIETVRQAGLDLQVGVVQTAYANGNSTHYLRDSLQVPVAFTQTGVKHLHHKAEEYDIGVYFEANGHGTVIFSTAARNTIRNATHGDAKALHILRSLINVINETVGDAISDMLVVLGVLAHRQWALADWDALYKDLPSRLVKVVVGNRHAFKTINADTQLEEPADLQARIDAEVAKVSRGRSFVRPSGTEDVVRVYAEAETREECDTLAYTVAGLVFDLAGGVGERPAEFL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GG745328
EMBL· GenBank· DDBJ
KNE55019.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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