A0A0L0GVM9 · A0A0L0GVM9_9ENTR
- ProteinVitamin B12 transporter BtuB
- GenebtuB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids611 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 85 | cyanocob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 110-111 | cyanocob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 198 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 207 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 209 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 209 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 211 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 211 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 245 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 246 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 246 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 247 | cyanocob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 258 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 306 | cyanocob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 514 | cyanocob(III)alamin (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell outer membrane | |
Cellular Component | pore complex | |
Molecular Function | ABC-type vitamin B12 transporter activity | |
Molecular Function | metal ion binding | |
Molecular Function | porin activity | |
Biological Process | monoatomic ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameVitamin B12 transporter BtuB
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Trabulsiella
Accessions
- Primary accessionA0A0L0GVM9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell outer membrane ; Multi-pass membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-20 | ||||
Chain | PRO_5008990847 | 21-611 | Vitamin B12 transporter BtuB | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 26-33 | TonB box | |||
Motif | 27-33 | TonB box | |||
Domain | 40-146 | TonB-dependent receptor plug | |||
Domain | 227-585 | TonB-dependent receptor-like beta-barrel | |||
Motif | 594-611 | TonB C-terminal box | |||
Sequence similarities
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length611
- Mass (Da)68,076
- Last updated2015-11-11 v1
- Checksum775F0CF078200C91
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JNGI01000069 EMBL· GenBank· DDBJ | KNC92864.1 EMBL· GenBank· DDBJ | Genomic DNA |