A0A0L0GVM9 · A0A0L0GVM9_9ENTR

Function

function

Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

161150100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site85cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site110-111cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site198Ca2+ 1 (UniProtKB | ChEBI)
Binding site207Ca2+ 1 (UniProtKB | ChEBI)
Binding site209Ca2+ 2 (UniProtKB | ChEBI)
Binding site209Ca2+ 1 (UniProtKB | ChEBI)
Binding site211Ca2+ 2 (UniProtKB | ChEBI)
Binding site211Ca2+ 1 (UniProtKB | ChEBI)
Binding site245Ca2+ 2 (UniProtKB | ChEBI)
Binding site246Ca2+ 2 (UniProtKB | ChEBI)
Binding site246Ca2+ 1 (UniProtKB | ChEBI)
Binding site247cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site258Ca2+ 2 (UniProtKB | ChEBI)
Binding site306cyanocob(III)alamin (UniProtKB | ChEBI)
Binding site514cyanocob(III)alamin (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell outer membrane
Cellular Componentpore complex
Molecular FunctionABC-type vitamin B12 transporter activity
Molecular Functionmetal ion binding
Molecular Functionporin activity
Biological Processmonoatomic ion transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Vitamin B12 transporter BtuB
  • Alternative names
    • Cobalamin receptor
    • Outer membrane cobalamin translocator

Gene names

    • Name
      btuB
    • ORF names
      GM31_21715

Organism names

  • Taxonomic identifier
  • Strain
    • 12
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Trabulsiella

Accessions

  • Primary accession
    A0A0L0GVM9

Proteomes

Subcellular Location

Cell outer membrane
; Multi-pass membrane protein

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_500899084721-611Vitamin B12 transporter BtuB

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for motif, domain.

Type
IDPosition(s)Description
Motif26-33TonB box
Motif27-33TonB box
Domain40-146TonB-dependent receptor plug
Domain227-585TonB-dependent receptor-like beta-barrel
Motif594-611TonB C-terminal box

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    611
  • Mass (Da)
    68,076
  • Last updated
    2015-11-11 v1
  • Checksum
    775F0CF078200C91
MIKKVSLWTALSATAFSVWAQDATPDTLVVTANRFQQPVNTVLAPTSVVTREDIERWQAKSVEEIMQRLPGVDIAQSGGLGAQSSFYIRGTESRHVLVLIDGIPLNNAGISNAPDLSQIPTSLIQRIEYIRGPRSALYGSDAIGGVINIITGRDKPGAEISAGVGTHGYQSYDGAFQQEIDKTKITMGGNYTYTRGFDIGANDAPPQPDRDGFMSKSLFGSVEQQLTDNLSGFVRGYGYDNRTAYDGYASYTADGTPDTRQLYSQNWDTGLRFNQGIYQSQLVAGYGRSKDINYDPSKGRYDDSATIDDVKQYTAQWLNNFTVGHGNIGAGIDWQKQKTQAGTGYLEKGYEQRNTGLFVSAMQQFDSVTLEAAARRDDNSNFGDHGTWQTSAAWEFIEGYRIIGSYGTAYKAPTMSQIHSANYGNPDLKPEESKQWEGGFEGLTGPVNWRISAYRNDVDNLIGYDANYRFYNVDKARIEGIEATAQFDTGPLAHQISYDYVDPRNANTNEVLKRRSKQQVKYQLDWQVWDLAWNLAYRYLGTRYDDDFSAYPTREVKLGGVSLWDVAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JNGI01000069
EMBL· GenBank· DDBJ
KNC92864.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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