A0A0L0CIZ3 · A0A0L0CIZ3_LUCCU

Function

function

Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine.
    EC:2.3.2.31 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

Features

Showing features for active site.

148050100150200250300350400450
TypeIDPosition(s)Description
Active site447

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentendoplasmic reticulum
Cellular ComponentGolgi apparatus
Cellular Componentmitochondrion
Cellular Componentubiquitin ligase complex
Molecular Functionubiquitin conjugating enzyme binding
Molecular Functionubiquitin protein ligase activity
Molecular Functionzinc ion binding
Biological Processautophagy of mitochondrion
Biological Processnegative regulation of protein phosphorylation
Biological Processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Processprotein polyubiquitination
Biological Processregulation of apoptotic process
Biological Processregulation of cellular response to oxidative stress
Biological Processregulation of mitochondrion organization
Biological Processubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    E3 ubiquitin-protein ligase parkin
  • EC number

Gene names

    • ORF names
      FF38_06888

Organism names

Accessions

  • Primary accession
    A0A0L0CIZ3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Forms an E3 ubiquitin ligase complex.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain30-99Ubiquitin-like
Domain253-480RING-type

Sequence similarities

Belongs to the RBR family. Parkin subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    480
  • Mass (Da)
    54,050
  • Last updated
    2015-11-11 v1
  • Checksum
    75B5DDD8B4036C7C
MSFLINLIKAFIDKMLALLSFGSKTITNTLSIYVKTNTGRTLSVNLEPKWDIKNVKEIVAPQLGLQPEEVKIIFAGKELSDATTIEECDLGQQSILHAIQARPVQQRKRLYSTVAEEEPSEEQPSKPLCETLVDLQLLSEERSNIPEENRERSKAHFYVHCSQCNKLCKGKLRVRCSLCKGGAFTVHRDPECWDDVLKSRRIRGHCESLEIACVDNDIGDPPFAEFYFKCAEHISGGEKDFAAPLNLIKINIKDIPCLACTDVSDTVLVFPCESKHVTCIECFLHYCRSRLMERQFMPHPDIGYTLACPAGCENSFIEEIHHFKLLTREEYERYQRFATEEYVLQAGGVLCPQPGCGMGLLVEPDCKKVTCQNGCGYVFCRNCLQGYHLGDCLPENGTGNTTGSCEYAVDPNRAAEARWDEASNVTIKVSTKPCPKCRTPTERDGGCMHMVCTRAGCGFEWCWVCQTEWTRDCMGAHWFG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JRES01000418
EMBL· GenBank· DDBJ
KNC31434.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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