A0A0L0CF23 · A0A0L0CF23_LUCCU
- ProteinProbable methylthioribulose-1-phosphate dehydratase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids224 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
Catalytic activity
- 5-(methylsulfanyl)ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | methylthioribulose 1-phosphate dehydratase activity | |
Molecular Function | zinc ion binding | |
Biological Process | L-methionine salvage from methylthioadenosine | |
Biological Process | L-methionine salvage from S-adenosylmethionine |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable methylthioribulose-1-phosphate dehydratase
- EC number
- Short namesMTRu-1-P dehydratase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Oestroidea > Calliphoridae > Luciliinae > Lucilia
Accessions
- Primary accessionA0A0L0CF23
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 15-211 | Class II aldolase/adducin N-terminal | ||||
Sequence: KLIPALCQQFYHLGWVTGTGGGISIKLNNEIYIAPSGVQKERILPEDLFVQDEEGKDIQIPPDYKHLSKSQCTPLFMLAYRHRNAGAVIHTHSQHAVMATLLWPGEEFRCTHLEMIKGIFDDESKRYLRYDEKLVVPIIENTPFERDLADSMYAAMMKYPSCSAILVRRHGVYVWGATWEKAKTMAECYDYLFSVAV |
Sequence similarities
Belongs to the aldolase class II family. Adducin subfamily.
Belongs to the aldolase class II family. MtnB subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length224
- Mass (Da)25,701
- Last updated2015-11-11 v1
- ChecksumF054706CBB6DFBE6
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JRES01000487 EMBL· GenBank· DDBJ | KNC30841.1 EMBL· GenBank· DDBJ | Genomic DNA |