A0A0L0C647 · A0A0L0C647_LUCCU
- ProteinAlkyl hydroperoxide reductase C
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids187 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.
Catalytic activity
- [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O
RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3+ CHEBI:35924 = RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ CHEBI:30879 + CHEBI:15377
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 47 | Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | NADH-dependent peroxiredoxin activity | |
Molecular Function | thioredoxin peroxidase activity | |
Biological Process | cell redox homeostasis | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkyl hydroperoxide reductase C
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Oestroidea > Calliphoridae > Luciliinae > Lucilia
Accessions
- Primary accessionA0A0L0C647
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-157 | Thioredoxin | ||||
Sequence: SLINTQIKPFKNQAFKDGKFIEVTEKDVAGKWSVFFFYPADFTFVCPTELGDVADHYAEFQKMGVEIYSVSTDTHFTHKAWHESSETIGKIKYTMIGDPTGALTRNFENMREAEGLADRGTFVVDPQGIIQAIEITAEGIGRDAADLLRKVKAAQY |
Sequence similarities
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length187
- Mass (Da)20,711
- Last updated2015-11-11 v1
- Checksum06E189299D0A581E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JRES01000949 EMBL· GenBank· DDBJ | KNC26874.1 EMBL· GenBank· DDBJ | Genomic DNA |