A0A0L0BS33 · A0A0L0BS33_LUCCU
- ProteinNAD-dependent histone deacetylase Sir2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids900 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 390 | Proton acceptor | |||
Binding site | 398 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 401 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 422 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 425 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nuclear inner membrane | |
Cellular Component | nucleoplasm | |
Cellular Component | rDNA heterochromatin | |
Molecular Function | metal ion binding | |
Molecular Function | NAD+ binding | |
Molecular Function | NAD-dependent histone deacetylase activity | |
Molecular Function | p53 binding | |
Molecular Function | transcription corepressor activity | |
Molecular Function | transferase activity |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Oestroidea > Calliphoridae > Luciliinae > Lucilia
Accessions
- Primary accessionA0A0L0BS33
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 60-83 | Disordered | |||
Region | 112-202 | Disordered | |||
Compositional bias | 127-146 | Acidic residues | |||
Compositional bias | 147-162 | Polar residues | |||
Compositional bias | 171-185 | Acidic residues | |||
Domain | 263-542 | Deacetylase sirtuin-type | |||
Compositional bias | 755-774 | Acidic residues | |||
Region | 755-789 | Disordered | |||
Region | 823-900 | Disordered | |||
Compositional bias | 852-873 | Polar residues | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length900
- Mass (Da)100,562
- Last updated2015-11-11 v1
- ChecksumCF4BF7E56A3A44AF
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 127-146 | Acidic residues | |||
Compositional bias | 147-162 | Polar residues | |||
Compositional bias | 171-185 | Acidic residues | |||
Compositional bias | 755-774 | Acidic residues | |||
Compositional bias | 852-873 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JRES01001454 EMBL· GenBank· DDBJ | KNC22852.1 EMBL· GenBank· DDBJ | Genomic DNA |