A0A0K9NGZ7 · A0A0K9NGZ7_ZOSMR
- ProteinMalate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids352 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (S)-malate + NAD+ = oxaloacetate + NADH + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 46-52 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: GAAGGIG | ||||||
Binding site | 72 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 119 | substrate | ||||
Sequence: R | ||||||
Binding site | 125 | substrate | ||||
Sequence: R | ||||||
Binding site | 132 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 155-157 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: ISN | ||||||
Binding site | 157 | substrate | ||||
Sequence: N | ||||||
Binding site | 191 | substrate | ||||
Sequence: R | ||||||
Active site | 215 | Proton acceptor | ||||
Sequence: H | ||||||
Binding site | 266 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: M |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | peroxisome | |
Molecular Function | L-malate dehydrogenase (NAD+) activity | |
Biological Process | glyoxylate cycle | |
Biological Process | malate metabolic process | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMalate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Zosteraceae > Zostera
Accessions
- Primary accessionA0A0K9NGZ7
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 41-183 | Lactate/malate dehydrogenase N-terminal | ||||
Sequence: KVAILGAAGGIGQSLSLLMKINPLVSVLHLYDVVNTPGVTADISHMDTNAVVRGFLGQQQLENALTGMDLVIIPAGVPRKPGMTRDDLFKINAGIVRTLCEGITMYCPHTVVNLISNPVNSTVPIAAEVFKKAGTYNPKRLLG | ||||||
Domain | 185-348 | Lactate/malate dehydrogenase C-terminal | ||||
Sequence: TMLDVVRANTFVAEVLGINPIDVDVPVIGGHAGTTILPLLSQVKPACSFTAEEINYLTNRIQNGGTEVVEAKAGAGSATLSMAFAASKFADACLRGLRGDANIVVCAFVDSQVTELPFFASKVRLGRAGVEEFYPLGPLNEYERSGLEIAKKELGQSIAKGTYF |
Sequence similarities
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length352
- Mass (Da)37,415
- Last updated2015-11-11 v1
- ChecksumE87D51C6A58C9AB0
Keywords
- Technical term