A0A0K9HBA3 · A0A0K9HBA3_9BACI

  • Protein
    Multifunctional fusion protein
  • Gene
    msrB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site14
Active site291Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrB
    • Synonyms
      msrA
    • ORF names
      AC623_19320

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • FJAT-27231
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    A0A0K9HBA3

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain180-302MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    318
  • Mass (Da)
    36,667
  • Last updated
    2015-11-11 v1
  • Checksum
    C2B060499D7CDF29
MAEQWKLATFAGGCFWCMVSPFDEQPGIKEVVSGYTGGHTENPTYEEVCSDTTGHYEAVQIKFDPAVFPYKKLVELFWQQIDPTDAGGQFNDRGLSYKTAIFYHDEEQKELAEASKTALEASGRFQKPVVTAILPAGPFYRAEEKHQHYYKKNPFHYNLYREGSGRAKFIRENWKNRKTDEQLRQELTPLQYEVTKHNATEPPFRNEYWNHIEEGIYVDIISGEPLFSSTDKYDAGCGWPSFTKPLRRIELEEKLDTSHGMRRIEVRAKTSDSHLGHVFDDGPGPDRARYCINSAALRFVPKDKLDEEGYGEFKSLFE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LFZU01000001
EMBL· GenBank· DDBJ
KMY55822.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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