A0A0K6GXN6 · A0A0K6GXN6_9NEIS
- ProteinPimeloyl-[acyl-carrier protein] methyl ester esterase
- GenebioH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids254 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
Catalytic activity
- 6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + methanol + H+
Pathway
Cofactor biosynthesis; biotin biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 19 | substrate | |||
Active site | 80 | Nucleophile | |||
Binding site | 80-81 | substrate | |||
Binding site | 142-146 | substrate | |||
Active site | 204 | ||||
Active site | 232 | ||||
Binding site | 232 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | pimelyl-[acyl-carrier protein] methyl ester esterase activity | |
Biological Process | biotin biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePimeloyl-[acyl-carrier protein] methyl ester esterase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Chromobacteriaceae > Gulbenkiania
Accessions
- Primary accessionA0A0K6GXN6
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 13-238 | AB hydrolase-1 | |||
Sequence similarities
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length254
- Mass (Da)27,385
- Last updated2015-11-11 v1
- Checksum76B804CFF9DF61FE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CYHA01000003 EMBL· GenBank· DDBJ | CUA83507.1 EMBL· GenBank· DDBJ | Genomic DNA |