A0A0K6GXN6 · A0A0K6GXN6_9NEIS

  • Protein
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • Gene
    bioH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

125420406080100120140160180200220240
Type
IDPosition(s)Description
Binding site19substrate
Active site80Nucleophile
Binding site80-81substrate
Binding site142-146substrate
Active site204
Active site232
Binding site232substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpimelyl-[acyl-carrier protein] methyl ester esterase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • ORF names
      Ga0061063_1778

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 17901
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Chromobacteriaceae > Gulbenkiania

Accessions

  • Primary accession
    A0A0K6GXN6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain13-238AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    254
  • Mass (Da)
    27,385
  • Last updated
    2015-11-11 v1
  • Checksum
    76B804CFF9DF61FE
MLHTETLGRGPDVVFLHGWGLHGGVFSRLARYLADSGLTVHLVDLPGHGHTPAEATFDIARIADQLALAFPLPVQVVGWSLGGLVAQHWAARHPDTVRSLSLVATSPRFVRSADWPHAQPREAIETVGHNLATDFEGTLRRFLALQTLGAPHARQTLEAMQSLLFAHGRPQGLMPALQALLEADARAVAPEIACPTGLFFGARDAITPTGAARWLAHTLPDARLHLFAQASHAPFLSHESDFIAALAPHLDRFA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CYHA01000003
EMBL· GenBank· DDBJ
CUA83507.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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