A0A0J9YVG2 · A0A0J9YVG2_MOUSE
- ProteinTranscription factor 4
- GeneTcf4
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids641 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | protein dimerization activity |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTranscription factor 4
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A0J9YVG2
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-41 | Polar residues | ||||
Sequence: MFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGTGGHP | ||||||
Region | 1-220 | Disordered | ||||
Sequence: MFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGTGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRENVQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNARRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNS | ||||||
Compositional bias | 62-99 | Polar residues | ||||
Sequence: GSHDNLSPPFVNSRIQSKTERGSYSSYGRENVQGCHQQ | ||||||
Compositional bias | 114-135 | Polar residues | ||||
Sequence: LSPTKPGSQYYQYSSNNARRRP | ||||||
Compositional bias | 159-220 | Polar residues | ||||
Sequence: VYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNS | ||||||
Compositional bias | 256-294 | Polar residues | ||||
Sequence: STFHRSGTNHYSTSSCTPPANGTDSIMANRGTGAAGSSQ | ||||||
Region | 256-296 | Disordered | ||||
Sequence: STFHRSGTNHYSTSSCTPPANGTDSIMANRGTGAAGSSQTG | ||||||
Region | 311-353 | Disordered | ||||
Sequence: HTNNSFSSNPSTPVGSPPSLSGTAVWSRNGGQASSSPNYEGPL | ||||||
Region | 440-544 | Disordered | ||||
Sequence: SLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANN | ||||||
Compositional bias | 443-462 | Polar residues | ||||
Sequence: PNQVPVPQLPVQSATSPDLN | ||||||
Compositional bias | 487-544 | Basic and acidic residues | ||||
Sequence: IKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANN | ||||||
Domain | 538-591 | BHLH | ||||
Sequence: ERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSL | ||||||
Region | 608-641 | Disordered | ||||
Sequence: KRREEEKVSSEPPPLSLAGPHPGMGDAANHMGQM |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length641
- Mass (Da)68,370
- Last updated2015-10-14 v1
- Checksum99D4BE827FF37CA2
Computationally mapped potential isoform sequences
There are 37 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q60722 | ITF2_MOUSE | Tcf4 | 670 | ||
A0A0J9YUF5 | A0A0J9YUF5_MOUSE | Tcf4 | 155 | ||
A0A0J9YUG4 | A0A0J9YUG4_MOUSE | Tcf4 | 537 | ||
A0A0J9YUK1 | A0A0J9YUK1_MOUSE | Tcf4 | 641 | ||
A0A0J9YUR0 | A0A0J9YUR0_MOUSE | Tcf4 | 121 | ||
A0A0J9YUS2 | A0A0J9YUS2_MOUSE | Tcf4 | 138 | ||
A0A0J9YV39 | A0A0J9YV39_MOUSE | Tcf4 | 184 | ||
A0A0J9YUP9 | A0A0J9YUP9_MOUSE | Tcf4 | 642 | ||
A0A0J9YUW9 | A0A0J9YUW9_MOUSE | Tcf4 | 107 | ||
A0A0J9YV50 | A0A0J9YV50_MOUSE | Tcf4 | 220 | ||
A0A0J9YV88 | A0A0J9YV88_MOUSE | Tcf4 | 145 | ||
A0A0J9YUT3 | A0A0J9YUT3_MOUSE | Tcf4 | 224 | ||
A0A0J9YUT7 | A0A0J9YUT7_MOUSE | Tcf4 | 320 | ||
A0A0J9YUX6 | A0A0J9YUX6_MOUSE | Tcf4 | 271 | ||
A0A0J9YUY3 | A0A0J9YUY3_MOUSE | Tcf4 | 119 | ||
A0A0J9YUZ0 | A0A0J9YUZ0_MOUSE | Tcf4 | 646 | ||
A0A0J9YV54 | A0A0J9YV54_MOUSE | Tcf4 | 220 | ||
A0A0J9YVC6 | A0A0J9YVC6_MOUSE | Tcf4 | 143 | ||
A0A0J9YVB3 | A0A0J9YVB3_MOUSE | Tcf4 | 167 | ||
A0A0J9YVG8 | A0A0J9YVG8_MOUSE | Tcf4 | 157 | ||
A0A0J9YVI1 | A0A0J9YVI1_MOUSE | Tcf4 | 610 | ||
E9Q8G4 | E9Q8G4_MOUSE | Tcf4 | 692 | ||
A0A0J9YTU7 | A0A0J9YTU7_MOUSE | Tcf4 | 541 | ||
A0A0J9YTR9 | A0A0J9YTR9_MOUSE | Tcf4 | 507 | ||
A0A0J9YTX3 | A0A0J9YTX3_MOUSE | Tcf4 | 100 | ||
A0A0J9YU37 | A0A0J9YU37_MOUSE | Tcf4 | 606 | ||
A0A0J9YU91 | A0A0J9YU91_MOUSE | Tcf4 | 172 | ||
A0A0J9YU99 | A0A0J9YU99_MOUSE | Tcf4 | 201 | ||
A0A0J9YTW1 | A0A0J9YTW1_MOUSE | Tcf4 | 587 | ||
A0A0J9YU75 | A0A0J9YU75_MOUSE | Tcf4 | 168 | ||
A0A0J9YU89 | A0A0J9YU89_MOUSE | Tcf4 | 198 | ||
Q8BPX7 | Q8BPX7_MOUSE | Tcf4 | 178 | ||
A0A1B0GXC8 | A0A1B0GXC8_MOUSE | Tcf4 | 106 | ||
Q91YV0 | Q91YV0_MOUSE | Tcf4 | 507 | ||
A0A140LJA2 | A0A140LJA2_MOUSE | Tcf4 | 80 | ||
A0A140LJC0 | A0A140LJC0_MOUSE | Tcf4 | 163 | ||
A0A140LIL4 | A0A140LIL4_MOUSE | Tcf4 | 117 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-41 | Polar residues | ||||
Sequence: MFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGTGGHP | ||||||
Compositional bias | 62-99 | Polar residues | ||||
Sequence: GSHDNLSPPFVNSRIQSKTERGSYSSYGRENVQGCHQQ | ||||||
Compositional bias | 114-135 | Polar residues | ||||
Sequence: LSPTKPGSQYYQYSSNNARRRP | ||||||
Compositional bias | 159-220 | Polar residues | ||||
Sequence: VYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNS | ||||||
Compositional bias | 256-294 | Polar residues | ||||
Sequence: STFHRSGTNHYSTSSCTPPANGTDSIMANRGTGAAGSSQ | ||||||
Compositional bias | 443-462 | Polar residues | ||||
Sequence: PNQVPVPQLPVQSATSPDLN | ||||||
Compositional bias | 487-544 | Basic and acidic residues | ||||
Sequence: IKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANN |
Keywords
- Technical term