A0A0J9WRV6 · A0A0J9WRV6_FUSO4
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids581 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 100 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 390 | Nucleophile | ||||
Sequence: T | ||||||
Binding site | 408-410 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: TVN | ||||||
Binding site | 432 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 460-461 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: SS | ||||||
Binding site | 483 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: G |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium oxysporum species complex
Accessions
- Primary accessionA0A0J9WRV6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-19 | |||||
Sequence: MKIPFLLLASSIHYISISA | ||||||
Chain | PRO_5005325299 | 20-581 | Glutathione hydrolase | |||
Sequence: SPIFEEFFSPSVGTRGAVASEAQECSYIGRDLLARGGNAVDAMIGTTFCVGVIGMYHSGIGGGGFMIVRDKKGNYEAIDFRESAPAAAFEDMYQGNVNGSIYGGLSVGVPGEVRGFEYAHKKYGSLPWKTVLQGAIKVAQDGFIVNADMARFIEKTIRDHHNFFVEDPSWAEDFTRNGMSFHSQRWDQGSQVAGQLIPEGEKMTRRRYARTLQAIAEHGADAFYTGAFAESMVKTIQETNGTITLDDYKNYDVISREVLHTEYKGYDVYGISSPAGGAVSLNILNTMNGYTHQDEDRNTTLHIYIEAMKFAYGARLHLGDPDFVDGVPELEHEMLNATTAEKIRRKIDPRKTQKIEKYDPDGIYSSDGHGTSHVVTADGDGMAVSLTTTVNLIFGSFLMDPLTGVILNNEMNDFSIPGVPNEFGFAPAEANFIRPNKRPLSSCTPLIVSNKDGSLFAVIGAAGGSRIISATTQVAWRVLTSPSWSIKDAVREPRVHNQLIPNTLLVEKKFSSYDVPSLVERGHNITWVDEGLSTVQALTRDSAGVFEVAPEPRQKNSGGVTL |
Structure
Sequence
- Sequence statusComplete
- Length581
- Mass (Da)63,519
- Last updated2015-10-14 v1
- ChecksumB099653D76A73AB1
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0J9VQM4 | A0A0J9VQM4_FUSO4 | FOXG_12796 | 565 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS231712 EMBL· GenBank· DDBJ | KNB13197.1 EMBL· GenBank· DDBJ | Genomic DNA |