A0A0J9WRV6 · A0A0J9WRV6_FUSO4

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site100L-glutamate (UniProtKB | ChEBI)
Active site390Nucleophile
Binding site408-410L-glutamate (UniProtKB | ChEBI)
Binding site432L-glutamate (UniProtKB | ChEBI)
Binding site460-461L-glutamate (UniProtKB | ChEBI)
Binding site483L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      FOXG_12796

Organism names

Accessions

  • Primary accession
    A0A0J9WRV6

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-19
ChainPRO_500532529920-581Glutathione hydrolase

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    581
  • Mass (Da)
    63,519
  • Last updated
    2015-10-14 v1
  • Checksum
    B099653D76A73AB1
MKIPFLLLASSIHYISISASPIFEEFFSPSVGTRGAVASEAQECSYIGRDLLARGGNAVDAMIGTTFCVGVIGMYHSGIGGGGFMIVRDKKGNYEAIDFRESAPAAAFEDMYQGNVNGSIYGGLSVGVPGEVRGFEYAHKKYGSLPWKTVLQGAIKVAQDGFIVNADMARFIEKTIRDHHNFFVEDPSWAEDFTRNGMSFHSQRWDQGSQVAGQLIPEGEKMTRRRYARTLQAIAEHGADAFYTGAFAESMVKTIQETNGTITLDDYKNYDVISREVLHTEYKGYDVYGISSPAGGAVSLNILNTMNGYTHQDEDRNTTLHIYIEAMKFAYGARLHLGDPDFVDGVPELEHEMLNATTAEKIRRKIDPRKTQKIEKYDPDGIYSSDGHGTSHVVTADGDGMAVSLTTTVNLIFGSFLMDPLTGVILNNEMNDFSIPGVPNEFGFAPAEANFIRPNKRPLSSCTPLIVSNKDGSLFAVIGAAGGSRIISATTQVAWRVLTSPSWSIKDAVREPRVHNQLIPNTLLVEKKFSSYDVPSLVERGHNITWVDEGLSTVQALTRDSAGVFEVAPEPRQKNSGGVTL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0J9VQM4A0A0J9VQM4_FUSO4FOXG_12796565

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS231712
EMBL· GenBank· DDBJ
KNB13197.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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