Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A0J9RT44 · A0A0J9RT44_DROSI

  • Protein
    Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
  • Gene
    Dsim\GD12815
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Protein modification; protein glycosylation.

Features

Showing features for binding site, active site, site.

147750100150200250300350400450
Type
IDPosition(s)Description
Binding site333Mn2+ (UniProtKB | ChEBI)
Active site416Proton donor/acceptor
Site455Interaction with galactose moiety of substrate glycoprotein

GO annotations

AspectTerm
Cellular ComponentGolgi membrane
Molecular Functionasioloorosomucoid beta-1,3-glucuronosyltransferase activity
Molecular Functiongalactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity
Molecular Functiongalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
Molecular Functionmetal ion binding
Molecular FunctionN-acetyllactosamine beta-1,3-glucuronosyltransferase activity
Biological Processcarbohydrate metabolic process
Biological Processcellular glucuronidation
Biological Processchondroitin sulfate proteoglycan biosynthetic process
Biological Processperipheral nervous system development
Biological Processprotein glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
  • EC number

Gene names

    • Name
      Dsim\GD12815
    • ORF names
      Dsimw501_GD12815

Organism names

  • Taxonomic identifier
  • Strain
    • W501
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    A0A0J9RT44

Proteomes

Subcellular Location

Golgi apparatus membrane
; Single-pass type II membrane protein
Membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane35-53Helical

Keywords

PTM/Processing

Keywords

Expression

Gene expression databases

    • FBgn0184541Expressed in adult organism and 3 other cell types or tissues

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region100-123Disordered
Region150-177Disordered

Sequence similarities

Belongs to the glycosyltransferase 43 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    477
  • Mass (Da)
    52,238
  • Last updated
    2015-10-14 v1
  • MD5 Checksum
    FBB8C1ABA2F8B37EB8FCD590C3B7BC96
MKGGNYTSLGTYSGINAGGNVAVAGKMSLGKSIKMYLTIFILTTCIYMALYQYHISREPFAASEVVKHQEKSSSYIASYLWSPISLLMANSSFNTINNSTTTSTTTTTAPTTPTTTTTGTVGSVGQKVGASSTSSIRMVSLAATIPSFKSESRSGSLGGHQKTATMKTSTTTTTTRTTASGLATTKLLATTRTTAKTSAKLSAATTPTASHMENGHKTRPTFVAASLPPPLYIITPTYRRPEQLAELTRLGYTLKHVVNLLWLVIEDANKTNPLVGHTLDRIGVPYEYMVAPMPEKYKQTKKAKPRGVSNRNRGLEYLREHATEGVLYFADDDNTYDISIFEQMRYISKVAMWPVGLVTKTGVSSPIIQAGKLVGYYDGWIGGRKYPVDMAGFAVSVKFLKERPNAQMPFKPGYEEDGFLRSLAPLDDAEIELLADECRDILTWHTQTKKNAPAQALNRTRYKNTNLEHIDRLLVRP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM002912
EMBL· GenBank· DDBJ
KMY98951.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help