A0A0J9RT44 · A0A0J9RT44_DROSI
- ProteinGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- GeneDsim\GD12815
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids477 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H+
Cofactor
Pathway
Protein modification; protein glycosylation.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 333 | Mn2+ (UniProtKB | ChEBI) | |||
Active site | 416 | Proton donor/acceptor | |||
Site | 455 | Interaction with galactose moiety of substrate glycoprotein | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Golgi membrane | |
Molecular Function | asioloorosomucoid beta-1,3-glucuronosyltransferase activity | |
Molecular Function | galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity | |
Molecular Function | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity | |
Molecular Function | metal ion binding | |
Molecular Function | N-acetyllactosamine beta-1,3-glucuronosyltransferase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | cellular glucuronidation | |
Biological Process | chondroitin sulfate proteoglycan biosynthetic process | |
Biological Process | peripheral nervous system development | |
Biological Process | protein glycosylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionA0A0J9RT44
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Single-pass type II membrane protein
Membrane ; Single-pass type II membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 35-53 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length477
- Mass (Da)52,238
- Last updated2015-10-14 v1
- MD5 ChecksumFBB8C1ABA2F8B37EB8FCD590C3B7BC96
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM002912 EMBL· GenBank· DDBJ | KMY98951.1 EMBL· GenBank· DDBJ | Genomic DNA |