A0A0J8CLA4 · A0A0J8CLA4_BETVV

Function

function

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenteukaryotic 43S preinitiation complex
Cellular Componenteukaryotic 48S preinitiation complex
Cellular Componenteukaryotic translation initiation factor 3 complex
Molecular FunctionmRNA binding
Molecular Functiontranslation initiation factor activity
Biological Processformation of cytoplasmic translation initiation complex

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Eukaryotic translation initiation factor 3 subunit A
  • Short names
    eIF3a
  • Alternative names
    • Eukaryotic translation initiation factor 3 subunit 10

Gene names

    • ORF names
      BVRB_4g076280

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > Caryophyllales > Chenopodiaceae > Betoideae > Beta

Accessions

  • Primary accession
    A0A0J8CLA4

Proteomes

Genome annotation databases

Subcellular Location

Interaction

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Family & Domains

Features

Showing features for coiled coil, domain, region, compositional bias.

TypeIDPosition(s)Description
Coiled coil93-120
Domain316-513PCI
Region589-610Disordered
Compositional bias803-854Basic and acidic residues
Region803-976Disordered
Compositional bias924-951Basic and acidic residues
Compositional bias953-976Polar residues

Sequence similarities

Belongs to the eIF-3 subunit A family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    976
  • Mass (Da)
    113,934
  • Last updated
    2015-10-14 v1
  • Checksum
    DFFFB33F6CC640B4
MSTFAKPENALKRAEELINVGQKQDALQALHDLITSKRYRAWQKMLEKIMFKYIELCVDMRKGRYAKDGLIQYRIVCQQVNVNSLEEVIKHFMHLSTERAEVARNQAEALEEALDVEDLEADKRPEDLMLSYVSGEKGKDRSDRELVTPWFKFLWETYRTVLEILRNNSKLENLYAMTAHRAFQFCKQYKRTTEFRRLCEIIRNHLANLNKYKDQRDRPDLTAPESLQLYLDTRFEQLKIATELELWQEAFRSVEDIHGLMCMVKKTPKPSLMVVYYAKLTEIFWISGSHLYHAYAWLKLFLLQKNFNKNLSQKDLQTIASSVVLAALSVPPYDHTRGASHLELENEKERNMRMANLINFNLDPKPESREVLSRSALLLELVSKGVMSCVLPEVKDLYHLLEHEFLPLDLSIKVQPLLNKISKLGGKLASASSVPEVQLSKYVIALEKLATLRLLQQASQVYQTMTIESLSQMIPFFDFSTVEKISVDAVKHKFLTMKVDHMNGAVSFSILDLESDNLRNHLTVLAESLKKARSMIYPPLNKASKIGDTLPGLAEVVEKEHKKLLARKTIIEQRKEEQERQLLEKEREEELKRQQQQKTNEEAEQKRLASEYEKRKIQRIQKEIEERELEEAKALLQEKFGKKQKKPIIEGDKLTKQALMELALNEQLKEKQEMEKKLQKLGKQMDYLERAKREEAAPLIEAAYQQRLVEEQLLHEREQQLEVELSRQRHDGDLQEKNRLARVMENKKIFQEKVMSRRQSEFERLRQEREEHIQQIRLARRQEREAKRKMIFYLRSEEERLNRLREEEESRKREEAERKRKEEAERKAKLDEIAERQRQRERELDEKERLRKQQILAGDPAARSSETTARLQPEAVPVAAPAAAAAAAAVPTPGAPAPGKYVPRHLREKTVEAPISSQAPASESDRWGRREDRPPADKWRSDDRRSFGSGPDDRRSFGSSGSRSTWSSSRVPPRGS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias803-854Basic and acidic residues
Compositional bias924-951Basic and acidic residues
Compositional bias953-976Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KQ090068
EMBL· GenBank· DDBJ
KMT14272.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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