A0A0J6LD81 · A0A0J6LD81_9PSED
- ProteinDeferrochelatase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids439 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
Catalytic activity
- heme b + 2 H+ = protoporphyrin IX + Fe2+This reaction proceeds in the forward direction.
Cofactor
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell envelope | |
Cellular Component | cytosol | |
Cellular Component | periplasmic space | |
Molecular Function | ferrochelatase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Molecular Function | peroxidase activity | |
Biological Process | iron import into cell |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDeferrochelatase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A0J6LD81
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-40 | ||||
Chain | PRO_5014489251 | 41-439 | Deferrochelatase | ||
Interaction
Subunit
Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 47-72 | Disordered | |||
Compositional bias | 56-66 | Basic and acidic residues | |||
Domain | 69-219 | Dyp-type peroxidase N-terminal | |||
Region | 221-253 | Disordered | |||
Domain | 236-418 | Dyp-type peroxidase C-terminal | |||
Region | 303-325 | Disordered | |||
Compositional bias | 315-325 | Basic and acidic residues | |||
Sequence similarities
Belongs to the DyP-type peroxidase family. EfeB subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length439
- Mass (Da)47,920
- Last updated2015-10-14 v1
- MD5 Checksum3E0637F0229A0726FE788C54A6C8F66A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 56-66 | Basic and acidic residues | |||
Compositional bias | 315-325 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JYLF01000009 EMBL· GenBank· DDBJ | KMN12321.1 EMBL· GenBank· DDBJ | Genomic DNA |