A0A0J6FSZ0 · A0A0J6FSZ0_COCPO
- ProteinCAAX prenyl protease
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids455 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Catalytic activity
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | CAAX-box protein processing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCAAX prenyl protease
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Onygenaceae > Coccidioides
Accessions
- Primary accessionA0A0J6FSZ0
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 123-148 | Helical | ||||
Sequence: LVFVFTFNLITTLLSIPVSYYSTFVL | ||||||
Transmembrane | 169-189 | Helical | ||||
Sequence: GQMLGVVLGAPIISAILKIVQ | ||||||
Transmembrane | 195-222 | Helical | ||||
Sequence: FFYYLWLFGMFVQLFAITIYPIAILPLF | ||||||
Transmembrane | 310-329 | Helical | ||||
Sequence: LFGIAQFHMFYIFALFSAFI |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 40-224 | CAAX prenyl protease 1 N-terminal | ||||
Sequence: QYRILQQKKPPKVLEGEVSQEVFDKSQAYGRAKAKFGFVSGLYSQIQNLAFIYYDALPKLWAVTGLWLTRYLPERFQGEITHTLVFVFTFNLITTLLSIPVSYYSTFVLEEKFGFNKQTVKLWVSDMLKGQMLGVVLGAPIISAILKIVQKTGTSFFYYLWLFGMFVQLFAITIYPIAILPLFNK | ||||||
Domain | 230-430 | Peptidase M48 | ||||
Sequence: PGTLKTGVEALAQKLQFPLKELYVIDGSKRSAHSNAYFYGLPWKKHIVIYDTLIEKSEPEEVVAVLSHELGHWSLSHTTKLFGIAQFHMFYIFALFSAFISNKSLYNSFGFHDEYPIMIGFLLFSDALAPMDAIVKLLMNILSRKFEFEADAFAVKLGYSAELARSLLKLQIQNLSTMDADWMYASYHYSHPILPERLGAL |
Sequence similarities
Belongs to the peptidase M48A family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length455
- Mass (Da)51,990
- Last updated2015-10-14 v1
- Checksum05E7CD35A5894AF8