A0A0J6F6X4 · A0A0J6F6X4_COCPO
- ProteinNeutral protease 2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids352 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine. May be involved in virulence.
Catalytic activity
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 303 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 304 | ||||
Binding site | 307 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 318 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNeutral protease 2
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Onygenaceae > Coccidioides
Accessions
- Primary accessionA0A0J6F6X4
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-16 | ||||
Chain | PRO_5005119728 | 17-352 | Neutral protease 2 | ||
Disulfide bond | 182↔254 | ||||
Disulfide bond | 261↔279 | ||||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length352
- Mass (Da)38,494
- Last updated2015-10-14 v1
- MD5 ChecksumEB45935591D62F3CFE8D3CB70E43A10F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS268111 EMBL· GenBank· DDBJ | KMM68696.1 EMBL· GenBank· DDBJ | Genomic DNA |