A0A0J6EVR4 · A0A0J6EVR4_9BACI
- ProteinCytochrome c oxidase subunit 1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids623 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
Catalytic activity
- 4 Fe(II)-[cytochrome c] + O2 + 8 H+(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H+(out)
4 RHEA-COMP:10350 + CHEBI:15379 + 8 H+ (in)CHEBI:15378= 4 RHEA-COMP:14399 + 2 CHEBI:15377 + 4 H+ (out)CHEBI:15378
Pathway
Energy metabolism; oxidative phosphorylation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | cytochrome-c oxidase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | electron transport coupled proton transport | |
Biological Process | oxidative phosphorylation | |
Biological Process | respiratory electron transport chain |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytochrome c oxidase subunit 1
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionA0A0J6EVR4
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 28-49 | Helical | ||||
Sequence: AVLYLVAGGFFFVLGGIEAMMI | ||||||
Transmembrane | 69-94 | Helical | ||||
Sequence: IMTMHGTTMIFLAAMPLLFALMNAVV | ||||||
Transmembrane | 106-129 | Helical | ||||
Sequence: PFLNSLGFWLFLFGGIFLNLSWFL | ||||||
Transmembrane | 154-180 | Helical | ||||
Sequence: FFVLGLQISGIGTLIAGINFIATIITM | ||||||
Transmembrane | 192-219 | Helical | ||||
Sequence: LFTWTTFVSSSLILFAFPPLTVGIALLM | ||||||
Transmembrane | 239-263 | Helical | ||||
Sequence: IWEHLFWIFGHPEVYILVLPAFGIF | ||||||
Transmembrane | 275-296 | Helical | ||||
Sequence: LFGYSSMVFATVLIGFLGFMVW | ||||||
Transmembrane | 308-333 | Helical | ||||
Sequence: VANAIFAVATMAIAVPTGIKVFNWLL | ||||||
Transmembrane | 345-369 | Helical | ||||
Sequence: PMLYAVSFIPSFVLGGVTGVMLAAA | ||||||
Transmembrane | 381-405 | Helical | ||||
Sequence: VVAHFHYVIIGGVVFAILAGAHYWW | ||||||
Transmembrane | 417-439 | Helical | ||||
Sequence: LGKITFVLFFIGFHLTFFIQHWL | ||||||
Transmembrane | 459-484 | Helical | ||||
Sequence: TANMVSTIGAFLMAVAVIILVINIIA | ||||||
Transmembrane | 555-573 | Helical | ||||
Sequence: ILPFFISFGLFVSAFGFMY | ||||||
Transmembrane | 579-601 | Helical | ||||
Sequence: WGLPVILIGLGITFFSMLLRSVI |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length623
- Mass (Da)69,170
- Last updated2015-10-14 v1
- ChecksumF0937B1D801129D5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LECW02000021 EMBL· GenBank· DDBJ | KRT93423.1 EMBL· GenBank· DDBJ | Genomic DNA |