A0A0J5FSW2 · A0A0J5FSW2_9GAMM
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids242 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Allosterically activated by GTP. Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 15-18 | ATP (UniProtKB | ChEBI) | |||
Binding site | 57 | UMP (UniProtKB | ChEBI) | |||
Binding site | 58 | ATP (UniProtKB | ChEBI) | |||
Binding site | 62 | ATP (UniProtKB | ChEBI) | |||
Binding site | 77 | UMP (UniProtKB | ChEBI) | |||
Binding site | 138-145 | UMP (UniProtKB | ChEBI) | |||
Binding site | 165 | ATP (UniProtKB | ChEBI) | |||
Binding site | 171 | ATP (UniProtKB | ChEBI) | |||
Binding site | 174 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Xenorhabdus
Accessions
- Primary accessionA0A0J5FSW2
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 11-219 | Aspartate/glutamate/uridylate kinase | |||
Region | 23-28 | Involved in allosteric activation by GTP | |||
Sequence similarities
Belongs to the UMP kinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length242
- Mass (Da)26,294
- Last updated2015-10-14 v1
- MD5 Checksum9E431A857C64A4C816DD76A69A344650
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LFCV01000061 EMBL· GenBank· DDBJ | KMJ45224.1 EMBL· GenBank· DDBJ | Genomic DNA |