A0A0J5FPC5 · A0A0J5FPC5_9GAMM
- ProteinATP-dependent DNA helicase DinG
- GenedinG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids711 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase. Unwinds D-loops, R-loops, forked DNA and G-quadruplex DNA.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
- Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction. This creates two antiparallel DNA single strands (ssDNA). The leading ssDNA polymer is the template for DNA polymerase III holoenzyme which synthesizes a continuous strand.
Cofactor
Note: Binds 1 [4Fe-4S] cluster.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 120 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 194 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 199 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 205 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Molecular Function | DNA/RNA helicase activity | |
Molecular Function | isomerase activity | |
Molecular Function | metal ion binding | |
Biological Process | DNA repair | |
Biological Process | SOS response |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase DinG
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Xenorhabdus
Accessions
- Primary accessionA0A0J5FPC5
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 17-294 | Helicase ATP-binding | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length711
- Mass (Da)81,313
- Last updated2015-10-14 v1
- MD5 ChecksumA8D777B6189DD15AC16AC784D4AF02BC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LFCV01000144 EMBL· GenBank· DDBJ | KMJ43807.1 EMBL· GenBank· DDBJ | Genomic DNA |